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6myFF-Lf3iY • Use These 6 Foods Hacks To Heal The Body, Starve Cancer & Burn Fat | Dr. William Li
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Kind: captions Language: en dark chocolate oh you're speaking my language now okay so dark can you eat can you eat too much dark chocolate that's the question you know I I have never seen anything about an overdose of cacao but I will tell you that cacao has been shown to actually double the number of stem cells flowing in your bloodstream just by having two cups of hot chocolate made with 80% High flavanol chocolate dark chocolate come on yeah it's been done in people 60 year olds with heart disease so wait what happens when you when you drink or you you eat this dark chocolate what happens yeah the polyphenols in this dark chocolate that we we know what they are they're called Pro entho in so I'm a scientist so my job is to actually know what are what the inside chemicals actually are these are natural chemicals all right most people don't need to know that but you drink it it tastes good that's all you need to know but but I'll tell you these natural chemicals found in cacao actually trigger a reaction in your body so that they call out the stem cells so it is literally like bees flying out of a hive can double the number of stem cells and what's the what's the Practical impact well there was a study done uh at UCSF in San Francisco that looked at 60y old men with heart disease so these are people whose blood vessels were already not doing so well and blood flow wasn't going so well either and their blood vessels were kind of sick that's kind of the definition of heart disease by having the stem cells coming out they were able to actually double the resiliency the function of their blood vessels so they they got better rebound they better agility um their their blood vessels are in better shape because their stem cells are regenerating their circulation wow so this is human studies right like most most of the time you hear about scientists talking about rats or mice or cells I'm talking about human studies and that's kind of where we are with food is medicine it's not the kind of like the guesswork like we can do serious research to get down to exactly what's actually happening at the human level so that's the second Health defense systems okay third one third one is our gut microbiome now people have been talking about gut health and microbiome it's almost like a buzzword these days and people are saying well can actually scoop your poop and we can actually measure your microbiome and we can tell you what you need to eat and what you know need to eat again I'm a scientist so I will tell you that there are 39 trillion bacteria in our in the typical body that's more stars than in a night sky all right wow so we barely understand uh the gut bacteria but what we do know is that this gut bacteria actually controls our metabolism communicates with our brain um actually can help us heal from the inside out and very importantly our gut bacteria basically lives you if you think of your gut like a like a garden hose it's a tube and you were to cut a garden hose in half and you look inside it there's a lining okay uh the bacteria is inside the hose but inside the wall of the garden hose that's where your immune system 70% of our immune system lives inside our gut so our gut bacteria 7% so so if you're feeding your gut a lot of bad foods it's po you're poisoning your immune system you're preventing your gut bacteria now I'll tell you what's interesting about the gut bacteria your gut bacteria talks to the immune system right through the walls of the of your gut immune system is in there 70% right like a jelly roll like a like the jelly and a jelly roll and the gut bacteria is inside so think about like a college student in a freshman dorm they talking to their Roommate by pounding on the wall right what do you want what kind of pizza do you want all right and they can answer you and that's basically what our gut bacteria says to our uh our immune system so we got to keep that gut healthy by the way interestingly uh and I've done research on this um certain gut bacteria uh can actually signal to your brain it's a gut brain axis and cause your brain to release social hormones wow okay and can affect your mood so you know when you've got a crappy gut and you feel crummy in your gut I guarantee you like it's not just because you're irritated it's affecting your brain as well that's crazy yeah we had uh we had Dr Emer uh mayor on who always got the gut I think it's the gut brain connection or the gut immune connection or something like that so he's he's got a lot of great research on that yeah so well the key thing though is that food can actually help right siiz your gut health think of it like an ecosystem the grap barer Reef so certain foods can support the ecology the ecosystem the great berry reef and certain ones actually kill the coral all right and so our continuously want to keep it in good shape all the way through our lives and by the way even conditions like autism Al Alzheimer's and schizophrenia are all now seemingly connected to our gut bacteria really yeah now is there a way if someone has those are they pretty easy to reverse though or is that hard we're we're well listen we're we're just figuring this out because right now medically we prescribe medications uh to try to treat those things and a lot of times those medications just blunt the symptoms okay they cover up the symptoms they don't get at the underly cause now we don't know exactly how the gut bacteria communicates with the brain completely yet yet but there's one giant nerve called the vagus nerve it's like a giant shoe it's about the thickness of a shoelace and it hangs from our brain all the way down into our gut okay goes right near wraps on our esophagus on the way down and our we think the gut bacteria basically sends text messages up to the brain through this big nerve okay so the key though is that foods can actually influence our gut bacteria either good bacteria or bad bacteria so that's important uh so that's that's a third Health defense system okay okay so the fir anog Genesis number one yes stem cells number two cells gut microbiome number three okay the fourth one number four our DNA now if you watch CSI DNA is just sort of like a genetic fingerprint a code that you can find on a crime scene or if you're actually trying to do ancestry look for your ancestors you figure out how how much of you is Neanderthal right I think I was 1% Neanderthal when I did it yes uh so the the the key though is it's DNA is a lot more than our genetic code it actually protects us from the environment now what am I what do I mean by that well you know how if we are exposed to uh we get sunburn ultraviolet light you damage your DNA and what happens cancer skin cancer right um if you inhale Lots of fumes from a chemical plant it's going to actually damage your DNA in your lungs you get lung cancer right but think about it if you are in Los Angeles and you're driving on the I 10 or if you're actually um uh just walking on a beach uh uh you are actually getting ultraviolet radiation so how come we don't get skin cancer all the time because our DNA is hardwired to fix itself from damage and so the DNA is a protective mechanism from the environment I always tell people when you're pumping gas if you still drive a gas vehicle as opposed to an e um I always ask people do you stand upwind or downwind what do you do are you upwind or downwind do you know I mean up up uh well upwind right so you're not getting the the fumes in is that what you mean right right right yeah well if you're standing downwind you can smell the fumes yes right and if you're smelling the fumes you are poisoning the DNA in your lung so how come we don't develop lung cancer after Pump and Gas because our DNA is hardwire to fix itself and so our DNA is sort of like a self-defense mechanism against the environment radon from your basement okay off gasing from the from the new car you just got or the Uber that you're riding in you know or the furniture that you got right so like it this is this is this incredible defense mechanism against our environment and then and foods can actually speed up the repair help fix holes that are in our DNA and then the other kind of PS the resistance for our DNA's defense is that there's something called a tiir I don't know if you've ever had anybody your show talk about tiir telr yeah yes these are these are see if you're at the longer the telr the the the longer you can live or something or they can right well well I'll tell you basically what the you know like to to give a to remind you to remind your listeners and viewers basically if your DNA is like a shoelace the Tere is like the little plastic cap at the end of the shoelace and over time that little cap kind of wears down just like on a shoelace and you know when that when that cap is gone man that your shoelace just falls apart yeah and that's what happens to our DNA so we need that cap that's called the tiir and it burns down like a life fuse so you know like Mission Impossible like the fuse right so this thing is burning down and when it burns down that's it your cell's done so what you want to do is to slow down your cellular aging and harsh things that you do to your body smoking cigarettes being in a couch potato being exposed to damaging oxidative stress actually just being stressed out um like we are now with this fraking pandemic um those things all shorten our teen they they burn the fuse faster stress but yeah but foods can slow it down and some foods can reverse it and lengthen the teir which is really cool for from an aging perspective right what are those what are those top three foods that help lengthen the telr green tea is one of them coffee I got I got a yeah it's amazing I got I got a little I used to live in Italy and I just got into this habit of drinking espresso H so I got a little cup here amazingly coffee actually lengthens your teir come on I I kid you not it's it's quite amazing um uh and uh leafy greens some of the polyphenols and leafy greens can also um slow down and some of actually look like they can lengthen a tiir as well so the key thing is that we you know we are not just helpless ponds of Aging we can actually do something about it and we can also fight against our environment um because look the the tax that we pay for being on planet Earth is we're exposed to stuff all the time and we need to we count on our body's Health defenses to fix it so that's a fourth defense and our fifth defense is our immune system which you know after two years over the last two years we all know how important our immune system is but what have I told you that your immune system is so powerful that when it's in its best shape even when you're 80 years old it is strong enough to fight cancer in fact it can even wipe out metastatic cancer that's spread all over your body That's How Strong your immune system is if you give it the chance and so here's what they immune system does it's like an army of super soldiers so uh Rangers seals as you know uh Marines Special Forces they're all they've all got these are all parts of the immune system all cells of the immune system and like the Special Forces they got their own weapons their own training their own tactics but they all work together for you know the collective good and what happens is that uh when you've got good strong defenses you can fight off Invaders from the outside bacteria and viruses for example and but it's not just outside Invaders you got inside Invaders as well and those little microscopic cancers are inside Invaders and so our immune system patrols our body okay cops on a be and they're looking for things that don't look right and you see that microscopic cancer that isn't can't grow because it doesn't have a blood vessel blood vessels feeding it androgenesis basically you the immune system goes there and takes them right out okay and takes a sniper shot and it's gone and so that's why we got to protect our immune system and there are lots of foods that can actually boost our immunity as well what would you be those what would be those top three that boost the immune system uh blueberries are a food that definitely boosts the immune system it's uh in young people as well as older people uh uh they boost the natural killer cells which is really cool um broccoli Sprouts can boost our immune system now these are the three these are like the three-day old Sprouts right okay um okay I mean okay here's something here's something most people don't know the big broccoli that when we eat broccoli we really you know our moms told us to eat the Treetops right those they're all thing you go to the freezer section of a grocery store and you buy some frozen broccoli and they all look the same they're all the same size that's not really what broccoli looks like if you go to the farmers market and you see a real broccoli is this gigantic stem with a little bit of Tree Top okay so what's in a broccoli it's called sorane so that's what gives broccoli that unique taste of broccoli it's a little sulfurous okay you got to put a little olive oil a little bit of garlic you know you could sauté it up okay so the suanes we've done research now looking at what what's in the Treetops and it turns out that these sophanes can starve cancer anti-androgenic help help your body cut off the blood supply to cancer broccoli Treet tops have it but guess what the stock of the broccoli has twice as much of the good stuff than the Treetops eat the stocks eat the stocks so man like if you don't want to eat if you don't want to sauté the stocks like a lot of cultures will just cut the stocks and saute them stick it in a blender you can make it into a smoothie or create make a soup out of it you know and so there's a lot of good things you can do put a little broccoli stem little oregano powder you know you can light light it right up a little turmeric it'll be really good um smoothie or a soup however here's the thing so this imagine this adult broccoli having these suanes well it turns out that these big broccoli plants used to be sprouts and the Sprouts pretty much were born or sprouted from the seed with all the suanes it's ever going to have all right so when it gets bigger it just gets distributed with the stock closer to the ground having more of it of course but the broccoli Sprouts have 100 times more wow of the suor of good stuff as a grownup broccoli so Sprouts broccoli Sprouts now Studies have been done to show that if you give people a flu shot people in a winter should get a flu shot so you don't get the flu all right just go to your drugstore to get one uh turns out that if you uh people are they did a study looking at people getting a flu shot and they gave half the people a little Shake made with broccoli sprouts and the other group just got a placebo and the people who got the broccoli sprout shake and a flu shot their beneficial response of their immune system is 22 Times Higher huh like it totally rocked if they actually had um a broccoli sprout shake so that's not food versus medicine that is food and Medicine which is really cool right interesting so we never want to throw we don't want to throw out the baby with a bath water we want to figure out how to make everything go work even better absolutely how do people melt the fat Dr Lee we are we're living in a time now where half the population almost is not just overweight but obese how do we solve this you know there's a lot to unpack in that question uh and I want I like to start by basically saying that my book Eat to beat your diet the title is a little bit of a trick title because it's not a diet book it's kind of an anti- diet book to say how we can actually improve our metabolism fight body fat and actually Elevate our health which is the real goal our Inner Health without ever having to go on a diet so saying that I can tell you that the whole idea about body fat it's loaded the word fat is actually a real loaded term in our society it's um associated with a lot of negative connotations right um when you think about fat it's usually something thing not that you don't want even if you walk by the putcher section of the grocery store you see that rind of fat around a steak you know you rather not have that right um but it turns out and this is what I write about that there's a new science to the body that gives us new appreciation of what fat actually does and how that connects to our metabolism in ways that we never thought actually existed so that fat itself is not a harmful entity when you've got too much and you got obesity it is harmful but up until that point actually fat believe it or not is a human organ it's an organ as important as your pancreas your liver your spleen your heart your lungs and it actually fulfills very very important purposes for our everyday Health connected to our metabolism and most people think about fat as something that grows on you and when you see it you don't like it so we all went through this we've all gone through this right get up in the morning take a shower step out of the shower out of the corner of your eye you see in the mirror lump or a bump that you don't want to be there right that's what makes you think about body fat but actually most people don't think about the fact that body fat actually existed before we were born and that leads us I'm a scientist so I like to ask origin stories where does fat come from and fat starts in the womb wow it starts in the womb and certainly the fat that we are packaged with in utero is not bad in any way it's probably probably is is performing a a vital function for Life yeah let me explain that to you so when your mom's egg met your dad's sperm and they got together formed ball of cells is going to be the future you right when they started to make tissue that will ultimately be your organs the first tissue that got laid down were your blood vessels because every organ needs circulation so that gets laid down first right so this is like building a house what goes down first well blood vessels get created when when we're created uh second tissue that gets laid down are nerves and why that because every organ needs signaling to be able to tell them what to do and so your nerves send those signals right seems pretty fun like if you were creating a blueprint of a body those would be the two things that you do and that's actually what happens third tissue that gets laid down surprising ly is fat body fat and they're called the fat cells are called adipose uh cells adapost is is another word for fat and they actually form blood vessels kind of like bubble wrap you know if you have a uh blood vessel and you were to wrap bubble wrap around it that's what fat looks like now what does fat do the and why is it wrapped around because fat cells atpo cells actually are fuel tanks um fat actually stores fuel Fuel and the fuel is absorbed from the blood gets into the fuel tank and so that makes total sense why they're actually located that way right so then after that the rest of our organs start to build all around that this just tells you how important fat is from the get-go fast for to n months baby is born what do you call a beautiful healthy baby a fat pudgy chubby baby right big fat cheeks round tummy uh think about it like they're arms and legs are like those balloons in a circus where you you know they make poodles out of it the clown makes it right literally they look like that right so there's something great important and healthful about fat in utero very important for survival and also when we're born right but we don't tend to think about fat in that context by by uh by sort of counter distinction if you actually saw a baby when they were born and they had chisel cheekbones like a fashion model and they had thin arms and long thin legs like like on a Runway you would be taken a back you'd go man there's something wrong with that baby yeah right and you'd be right okay so a fatless baby a thin baby lean baby is not well okay so this is my kind of reset for you to to rethinking body fat is actually one of the things that I write about like we need to have a complete uh reconceptualization and re and a new understanding of what fat actually does yeah so what is the what is the fat doing for the baby during that that stage of life okay what the fat is doing for the baby is actually a Continuum of what fat does for our healthy bodies for the rest of our lives and so this is sort of the the goodness of fat that's hidden beneath the kind of the perception of the Badness and the actual Badness so I'm not denying that excess body fat is harmful it's very harmful we're going to get into that in a second but before we talk about the harms it's so easy to jump into the demonization in the health and wellness space of things I'm a scientist I'm a doctor let's talk about the good stuff first so we can understand you know when does good become bad and that way we can know how to restore the good right that's I'm with you yeah okay so first of all fat as I mentioned to you is um an organ uh and it performs multiple functions as an organ what kind of organ is it turns out to be an endocrine organ uh produces hormones like your thyroid like your adrenal glands okay like your pancreas and that's an amazing thing because we don't normally think about our fat as an organ most organs are just a a chunk of something connected to tubes well Fat's actually a kind of organ that is distributed throughout our body and what does a fat produce as a endocrine organ it produces hormones 13 different hormones that are known currently wow all right and three of them I want to mention because I think it's important just to give some examples of what this hormonal function of fat actually is remember we're talking about health we're talking about healthy fat healthy body from baby to uh you know end of life the first hormone is leptin made by fat and many of you may have heard about leptin leptin is sort of the appetite controller right more leptin less appetite less leptin more appetite so it's kind of like a volume switch for your hunger all right and that's important because when your fat actually is controlling your brain to go search for food so you can load up on fuel because the fat cells are fuel tanks so you can kind of see how the so starts to fit together now all right now fat so that's one hormone most people may have heard of leptin before another hormone that people that have not heard about or at least very few people have heard about is called adiponectin adiponectin is another Fat hormone okay uh it's a very important one and it's completely concerned with helping your body gain energy from the food that you eat all right in fact it works as a partner with insulin which is a hormone that helps energy so let me tell you if I were to take a VI of your blood send it to a regular Hospital lab to analyze your hor your hormones your adiponectin levels and mine would be 1,000 times higher than any other hormone in your body wow higher than testosterone higher than thyroid hormone higher than cortisol anything else now why is that it's because because a ditin partners with insulin to make sure that the energy that you have from the food that we eat is efficiently absorbed into our bodies that's our metabolism it's part of our metabolism so good healthy levels of fat perform this function to bring in energy along with insulin it's very very important uh sort of as a foundation for our energy now there's a third hormone I want to mention it's called resistant resistan is like like the break to a dip ackon that's the Gas Pedal Gas Pedal goes down let's absorb lots of energy fast hard resistant is like whoa let me let's put on the break here a little bit less all right so you know most systems in the body are about balance okay leptin uh up less appetite leptin down more appetite adipine in down you actually have more efficient energy absorption uh resistant down the break actually pull back on energy absorption makes sense because we want to fine-tune our our Metabolism from day to day so that's one very important thing that normal healthy fat does it's a setup in the womb the babies start to do it right away and it continues throughout our lives this is how we normally function now a couple of other things that fat does as well besides being an endocrine organ it's a cushion now most people think that fat might be a uh like insulation kind of like blubber on a whale n it's more of a cushion think about fat like peanuts that you might pack you're something you're shipping across the country in yeah all right if we had no body fat all right and the most important body fat for the cushion actually is inside our frame packed inside our belly if you had no fat and you tripped on a rug and you fell on the ground your organs would burst open so fat actually has sort of a cushion uh role as well now the other thing that fat actually has a very important role on that's fascinating uh is that it's a space heater and a space heater so this isn't just passive you know like again like the blubber is just passive um the cushion is kind of passive but this is an active function just like the hormone instead of releasing hormones it releases heat wow now let me explain to you not all fat generates heat so the new science of the metabolism tells us broadly speaking there's two color two kinds of fat in our body there's white fat which is jiggly the white fat that's under the skin is meaning close to the skin we call it subcutaneous that's the stuff you see under your arm under your chin that's the muffin top all right to run your thighs and your butt that's the stuff that most people don't like want to get rid of um uh you know if and I have no problem with that I that's a good thing if you feel good by streamlining your body go for it yeah like that that's an important thing uh and too much of it is also bad for you but the other thing that's really important is that another kind of jiggly fat is actually packed inside your body that's the visceral fat we were talking about earlier now visceral fat doesn't care if you have a big siiz body like a weightlifter in the Olympics or a thin body like a javelin thrower in the Olympics it can grow inside and that fat is sort of like the peanuts for packing that we talked about except when it starts to grow excessively it goes from being a packing peanuts into turning into a baseball glove that wraps around your organs and chokes your your organs o and it can happen whether you're apparently thin or you obviously if you actually have excess weight all right that's white fat both not so good for you visceral fat deadly so both the subcutaneous fat and the visceral fat are white fat correct got it right now the other kind of fat that's not white fat the other kind it's called Brown fat you know you're starting to see and hear about Brown fat you know and you know she see online you see some advertising for it you know a lot of uh people in in the weightlifting world and bodybuilding World talk about Brown fat I'm not coming from that sector I'm I'm coming at this really as a scientist and a doctor and let me tell you something about Brown fed it's absolutely fascinating because only recently have we discovered that humans have not just a little brown fat but a lot of brown fat and brown fat is different than white fed because it's not jiggly it's not lumpy bumpy jiggly it's not under your arm and it's not definitely not subcutaneous you can't see it it's not under the skin Brown fat is paper thin wafer thin okay so think about it fat is thin wait a minute that seems to be a contradiction in terms but yeah Brown fat are thin sheets and it's not close to the skin you can't see it it's close to the Bone all right it's deep and it actually is plastered around our neck plastered underneath our breastbone around like a girdle around our our chest under our arm a little bit in the back a little bit in your belly scattered okay and that fat has space heater function wow it's like a nuclear plant that can fire up when it's stimulated in order to burn energy so it really actually activates your metabolism and as it does that it needs fuel right the space heater needs power it needs gas um it needs to get fuel where does it draw the fuel where does brown fat draw the fuel from Brown fat draws its fuel to burn from white fat so Brown fat is good fat that can fight white fat when it's bad fat fat versus fat another another totally interesting thing that you would you can actually think about fighting fat with fat it's like a civil war happening in your own body uh yeah exactly except that you basically they're all they all started out being friends and all started out creating kind of a peaceful Society yeah well they should I mean ideally we'll return to that so how do we then you've mentioned what brown fat does and you mentioned where it tends to uh habitate in the body how do we how do we Stoke that fire and how do we encourage its proliferation if it's so good for us can we even do that yeah well look I want to tell you a little story about how Brown fat in humans was discovered because it's so fascinating I I think that there's so much to be learned about the origin stories and the history of things because it just gives us a better appreciation that this isn't just a trend or fad this is something real that was discovered over time okay so in the um 1700s s uh there was a um uh a naturalist you know kind of somebody who studies nature named Conrad gestner he lives in Switzerland and he was really interested in understanding animals and the anatomy of animals so he he uh was actually taking a look at um a rodent that lived in the Swiss mountains uh that um uh would hibernate and he would catch one and dissect it and you know like they do in the old school days they would draw the organs and he found one organ that was between the shoulder blades and he didn't know what it was brown colored but didn't look like anything else that was out there well fast forward actually um uh a professor at UCLA took a look at that I mean over time and started to really we had there were more sophisticated lab tools and said you know what that brown thing actually is made out of fat and the idea of this is that they thought maybe it was something only in hibernating animals so then they started to find it in bats and other kind of animals that actually hibernate okay and they said well I wonder if it's in humans fast forward a little bit further they found it in babies human babies you know where they found it in human babies just like in this rodent in Switzerland they found it between the shoulder blades when babies are born there's a little lump of brown fat um that actually is there wow now what did they figure out the brown fat did in hibernating animals is that when the animals are uh surviving over the winter they need they need a space heater so Brown Fett fires up it keeps them warm all right now what now what about human babies why do we have that is it a relic of evolution um you know look babies are born in delivery Suites we can put them into incubators you know they're in warm homes uh why do we need them so the idea that was originally thought is you know it's just maybe vdu like an appendix all right which we know now it actually has a function because it actually Harbors gut microbiome as well all right so you don't want to be or your tonsils right like people used to say let's whip out the tonsils whip out the appendix no no no like that's they're actually form they're actually important components of our body all right so Brown fat and babies um is it vestigal no actually it serves a function and what they found is that and they thought well maybe maybe when the baby's grow up the B Brown fat just goes away just kind of melts away turns out that researchers in Boston were once looking at um a woman who came in with a tumor in her chest and they uh did a biopsy looked at the biopsy and it was made out of fat okay and in fact it was called a hibernoma because it resembled the hibernating animals Mass organ wow okay Ma meaning tumor and it wasn't malignant all right but what they thought they was really interesting is that when they scanned it using a pet scan which captures metabolic energy in other words what you deem to generate Heat this baby in this tumor this little tumor hibernoma this brown fat tumor lit up like a nuclear engine wow okay and it was only because we had pet scannings at that time that it could actually even be figured out so the researcher that did this uh in Boston Ronald Khan actually went back and said I wonder if there if this um signal uh exists in other pet scans met metabolic scans in other people so he went back and dug up thousands of other scans that were done and found yeah actually there are people that are showing this brown fat throughout their chest and we just missed it wow like it was there but we weren't looking for it so we just kind of ignored the signal but not everybody had it so what he then did is he said went back and said you know what it was in hibernating animals that they saw it way back when in the old days right Conrad gestner so he said let's go back and match the pet scans with the temperature of the day in which the scan was taken so we went back to the meteorological record and found every time a patient had a pet scan that shown Brown fat in the body it was on a cold day in the wintertime and on warm weather days it was cooler so this space heating fat function that lives in adults as well as baby as well as hibernating animals truly has a physiological function to help generate heat it is a space heater wow so much of your attention is focused on adding in you really want the audience to add in and the readers to add in and I'm curious about that of from your perspective of how you arrive there and how much does the balance come in terms of adding in versus as you were talking earlier with artificial sweeteners in the gut microbiome that there's certain foods that just by taking them out we allow the body to do what it does naturally how how do you think about that balance yeah well look first of all um I'm like most people I think uh when you tell me not to do something my brain goes well maybe maybe I'll do one more time you know maybe I'll try it and so there's a lot of human nature to um how we respond when somebody says something to take something away from you and human nature abhor deprivation and so one of the things is you know I think most of us like to have our quote cake and eat it too and so I always felt um when I was you know taking care of patients and trying to counsel them on things rather than tell them to remove things uh from their diet because that's really easy to do and there's plenty of people out there you know um scolding people you know fear guilt and shame is sort of like the the building blocks of traditional counseling about nutrition you know and makes you feel bad actually uh when somebody tells you you know like you're a bad person for eating junky food what I try to to is Empower people because I think people love to feel justified in what they love like and so in my book I read about 200 foods that all activate the body's Health defenses and I used to say I dare you to find in this 200 Foods something like like that I dare you to find review this foods and tell me that there's nothing that you like and most people actually find something in 200 foods that they actually like and I say well look start with this because what you like is already good for you so you're already way ahead of the game and if you can start add keep on adding things that you like and just understand this is that education knowledge piece what you like is good for you then you can love your food and love your health at exactly the same time and then this whole idea of anti- deprivation is that if you spend more time thinking about what to add to your body that's good for you you'll spend less time thinking about the bad stuff and more good things in your body uh kind of push out room for bad things and if you spend most of your time fortifying your body's Health defenses those five Health defenses angiogenesis stem cells microbiome DNA protection and Immunity with Foods honestly every now and then you're G to fall off the wagon you can eat something you really like or you really want to or you know everybody's eating around you and it's not that good for you that's all right your body's got you covered your health defenses are there as a shield so again you know like I I think that there's just a healthier way to navigate through your life these strict diets are don't work for a long time they're unsustainable so I'm all about how do you actually get people to feel like they're in control and what they like to do already is actually good for them now that's a great explanation it's you're crowding out the quote unquote bad I mean there really is no bad because the beautiful thing about it is that you know there's this term that's coming out now more with uh blood sugar and continuous glucose monitors and the idea is um you know metabolic flexibility that when you're doing when you have a diet that is maintaining a healthy blood sugar on a average basis then you go somewhere you you you want to enjoy something you enjoy that thing you're not having the stress of this thing is going to completely throw me off because your foundation is so healthy so resilient that you can enjoy some of these things because food is not just about fueling our body and avoiding disease it's all about the joy social aspects um breaking bread together so to speak and and that adds a lot to life including SE severely reducing stress and and I find that the healthier that I become with the foundation and having a ton of plant Foods inside of my um diet by volume I would still say most of the calories by by calorie it's still probably a little bit heavily reliant on uh you know the healthiest quality animal foods that I can find wild caught fish grass-fed steak you know things like that that'll throw in but by volume it's still plants when I have that base I also have less desire for these other things so instead of eating the whole croissant I was in Mexico City recently and we came by an incredible Bakery I just wanted a little taste I wanted to get the idea of it I had a little bit and I was like that's cool because I never feel deprived I never feel that I have to use willpower to say that I can't eat something or that it's bad for me no this is something that I can enjoy I get the point and then I can move on from there yeah you know I I I I know there's this you know Japanese saying harashi banme that basically says just eat 80% uh and then leave you know like like quit the clean play club and don't eat you know and just eat 80% of what your body would want I have another which I think is really healthy it's kind of like your own way to actually have caloric restriction which we know scientifically is good for you but I have another story to tell you um please I I I traveled to Asia after college and I was in China in Beijing and uh this is you know soon after China not too long after China opened up for for tourism so long you know this is many decades ago and I went to visit the Summer Palace and I've been back a few times um obviously this is way before the pandemic and um you can actually visit the Summer Palace where the dower Empress lived and and and basically this royalty of China basically is fed by Imperial chefs and you can it was a restaurant so I I I was honored to be um able to uh dine there and they they wanted to serve an imperial meal to show you what it was like back then so I'll tell you most of it was plant-based but they had 30 different types of dishes that came out in a in a dinner 30 okay and there's no way you can eat 30 dishes right I mean think about it you go to like a steakhouse there's no way you're going to eat 30 or you go to a vegetarian restaurant you're still not going to eat 30 meals so what I learned that was that's never left my mind was that you know food is pleasurable and and the way that the the approach was not to put a lot on the plate have a lot of different uh variety to really be able to stimulate the tast buuz get the enjoyment of the food make people feel like they could indulge and enjoy their meal and the dward your Empress would just eat with the Chopsticks just take one bite out of each plate okay um and just get a sampling and so that's what I realized with you when you're talking about the Quant I I it brought that back my memory back to me you know like you don't have to have the whole hog of whatever it is they're serving you can actually satisfy your Indulgence by having a taste of it savoring it like really try to enjoy it um and that way you know you if you and you give a little bit of time you don't it's not going to make you want to go back and and just Pig down on the whole thing you like learn how to enjoy the taste of something allows you to experience more without having to stuff yourself it's well said and I think for a lot of people who are listening here you know just like you gave the example about the broccoli and the broccoli Sprouts they they know food is powerful and we're all creatures of habit we get into buying the same sort of five you know vegetables that everybody ends up having corn potatoes you know all all those classic examples to which obviously have a lot of uh healthy properties as you highlight inside of your book but when we talk about variety and getting inspired that's what I really love about what you guys are doing with your course and and kind of extending out the book is you're giving even more inspiration more education so that people can get excited about wanting to go try something new so that you go into Whole Foods you go into Trader Joe's you go into your local supermarket wherever it is or shopping online and you're like wow I'm actually going to pick out this other food that I kind of overlook you know what's an example of one of those things that is an underrated food something that people Overlook and might not have as part of their normal routine but can have such a profound effect if they start including it in into their diet yeah I'll tell you a great one kiwis right so these sort of um I don't know baseball shaped a little smaller than baseball furry little brown things you cut them open they're beautiful and green with seeds starburst on the inside um I didn't use I I always like kiwi but I never really ate them very much but I started doing the research on them and kiwi is pretty amazing first of all it's a great source of vitamin C and fiber and the vitamin C actually has tremendous antioxidant effect and it can protect your DNA and Studies have been shown that actually if you eat one kiwi a day it'll protect your DNA against damage by about 60% if we ate three kiwis it would actually help your body build any damaged DNA back back um by about 60% and so here's something simple that you can peel cut up chop into a yogurt or just eat plain it's delicious um you can put it into a smoothie that actually has this amazing ability to actually protect your genetic material like you know that's that's so fundamental and it tastes great and not too sweet and it's got a little citrusy flavor then the other thing that's great about kiwi is that it's got it's packed with fiber now fiber as a is basically a kiwi is essentially a Prebiotic food its fiber feeds our gut microbiome and Studies have shown this is a study done in Singapore that show that just eating a kiwi even one kiwi overnight will start to change your gut microbiome favoring more healthy species of bacteria and so you know like I I always tell people like if I tell you something like that and you try a kiwi uh uh you know you can't unlearn what I just told you every time you see the Kiwi you're going to say you know what I know there's something good about it and then if you remember what that is that's really what I try to do with my with my course is really try to teach people how to make it second nature to make great choices and to be enthusiastic about it like I think most people are kind of intimidated by uh this is you know kind of like the whole philosophy behind my course people are intimidated by diets right to begin with they're a little yeah you know maybe I didn't do do so good in my life I I should do better you know it's always people go into a diet in order to try to get better and what I try to shift that Paradigm is look if you're serious about getting healthy and this is the time you want to actually do it it's not that difficult you just got to dive in engage you do want to be awake you need to be alert and you got to realize it's not about somebody feeding you a super food or a Super Supplement and that's all you got to take every day you know it's really about understanding more about you self- knowledge about how your own body works right like at some point we all figured out how our eyes work and how our lungs work and how our prostate works and our uterus figure this out this is like this is like the The Cutting Edge science you want evidence you want food as medicine and you want to know that it's not about memorizing food it's about memorizing how your body actually works and then recognizing our bodies actually work really well to complement certain foods and so what does a tomato do a well tomato complains lopine what does lopine do actually protects our prostate man that's a that's a really good thing also protects our breast that's a really great thing um you don't need to remember all the chemicals you just need to remember that that's the way to do it and then I try to get people to be passionate about cooking because you know one of the antidotes to unhealthy eating is really trying to get back into the kitchen and preparing your own meals you don't have to be a fancy Chef you don't even have to have a fancy pet you know if you can fry an egg you can actually cook healthy food and and that's what I try to do is to try to make people feel like lower your guard it it's not a problem you know you can actually learn how to do this and you know there's nothing more satisfying to me than to actually go out and you know find some great looking healthy Fresh Foods figure out how to cook them and and taste it myself like it's like you know like back in wood shop when you're in junior high school and you created your own toolbox like man that that's really cool I I made that and that's how I want get people to feel excited about um uh about food as medicine this is not hard it is not a burden it's not an onus this is something that you can do you can make for yourself it's powerful because you know we were started off this interview by talking about how again well-meaning well-intentioned uh researchers practitioners you know people that we look to as the voice of authority in a lot of key areas sometimes it's not the absence of evidence it's just the lack of awareness of the evidence that's there but also we as individuals call us consumers people that are in charge of Our Own Health that are just trying to live a happy life take care of our families we have to take on some of that burden I think in a way we have um and there's a there's a lot of layers to this but we expect a little bit too much from our doctors we expect a little bit too much from the Health Care Community they're just doing their best right they're just doing their best that they can so we have to remember that you know where we need help and thank the Lord for all the incredible medicines many of which you've been a part of you know developing that have given us healthier lives and extending lives as well too but on a day-to-day basis us getting educated is so key and Central because if you don't know or care enough then you become a victim of sort of the marketing and the marketing could be in the health world and the wellness world or the marketing could be towards Big food companies again all primarily well-intentioned we used to be a society that was dying of not enough food and that's where a lot of that marketing comes from but now we're dying of having too much of you know too much food and too much of especially the the wrong foods that that are there the ultr processed foods so empowering yourself empowering yourself with that knowledge it actually is the thing that makes the difference what would you say would be like five tips that you could share with the audience on how people can improve their diet quality yeah happy to give you the five tips but let me kind of frame this by saying there is so much negativity associated with food I'm coming at this from a completely different perspective I would say negativity was out there and also misperceptions and and lack of accurate information so I like to kind of turn the entire formula around and come at this with how do we not fear our food number one and number two how do we actually use the facts and the signs to really be able to inform uh how we can Embrace food instead and you know this has to do with my background as a physician as a scientist and as somebody who's actually been involved with biotechnology and developing cancer treatments and diabetes treatments and treatments for blindness for almost 30 years the reality is is that food in fact is really one of the most powerful Health Care interventions that we can do for ourselves and five tips I will give you right up front that could be really useful is and this is sort of you know really across the board for anyone who has to eat which is everyone I would give you the five general principles number one stay hydrated because dehydration actually makes everything in your body work harder and so if you want your food to work for you you actually want to make sure your body has enough water content to be able to keep all those metabolic processes functioning really well number two I would say eat what you like but make sure that most of what you eat and the priority majority of where your head goes when you're choosing something making good choices really falls in the category of what we call plant-based foods which is pretty broad I mean there are hundreds of foods that are plant-based and it doesn't have to be broccoli and kale it could be beans it could be mushrooms it could be onions it could be garlic all the things that you think hark back to those traditional delicious recipes that came from the grandmothers of the Mediterranean whether it's Italy or Greece or Spain or France or Asia whether it's Japan or China or Thailand I mean you know all those delicious things that you might see in a menu I want people to think about healthy eating as when you look at a menu or when you actually are shopping look for the things in the produce section first or look for the things that actually have vegetables in them they don't have to be the only thing but if you use that as a kind of a filter you're going to be doing something really good for you that's a second thing third I would say to the extent possible avoid ultr processed foods and we all have things that we like that we grew up with that are snacky type of foods and we all have lives that take us in different places in our communities or around the world even and we can't always get the healthiest food but what I wanted to kind of like emphasize is if you can cut down if not cut out Ultra processed foods things that actually have lots of artificial preservatives artificial colorings artificial flavorings you know those are the things that actually taste pretty good and we're kind of addicted to from marketing and from from our childhood so you've got we've got legitimate reasons why we like these things because they taste pretty good if you can cut down if not cut out those things that's actually going to tip your dietary pattern in your favor the other thing that I would actually say that would be really helpful is to try to avoid foods with added sugars whenever you can this is your regular soda this is actually even your diet soda which actually has artificial sweeteners added that mess up your gut health and your gut microbiome and actually throw your metabolism off kilter but stay away from added sugar because we can get a plenty of sugar from the regular Foods we eat but if you start stuffing candy bars you know the Habit we' had as kids right Halloween get that pillow and stuff it like a gunny sack and go out there and Peg out all night long look that's a lot of artificial sugar and even as adults we wind up actually snacking that way unconsciously and it actually overloads our metabolism that's a fourth thing and the fifth thing I would actually say is that I want to come back to beverages for a second you know besides water there's two other bever that I think are go-tos for health and one is tea could be green tea could be oong tea could be black tea and the other one is coffee remarkably you know water tea and coffee are the go-tos for beverage and health now what you add to them can make a big difference but you know those are five general rules that I think will take anybody Health towards a path of health and by the way you'll notice that I didn't give any absolutes and I didn't say things that are really unreasonable so that's probably a good place to start this conversation yeah I love that and I would imagine that the five tips that you shared probably go in line with what you would recommend for somebody as far as a dietary pattern to follow for longevity so I guess outside of making sure you're consuming a lot of plants drinking plenty of water limiting Ultra processed foods what are a few other like Staples that you think people should include within like a dietary pattern if they want to increase their longevity right okay so longevity means not only having more birthdays but also having good quality of life along the way right so we want a good healthy lifespan not just a long lifespan if you're gorked out you know at a 100 years old or you are blind 100 years old that would not be worth it so I think the key to longevity and you know this is such an important and popular topic I think and it's really driven by science there's a lot of really exciting things about longevity I want to make sure people don't forget that want to we want to actually be able to enjoy our lives even as we live longer nobody wants to add more miserable years to their life all right so having said that one are the things that are important to us and I'm going to give you some concrete food things but I you know what you're going to hear me talk about is the framing because I think a lot of times when we hear about nutrition or food is medicine we hear about individual substances individual Foods individual recommendations without getting to context so I think context is important how do we actually maintain good later years in our life if we want to expand them our brains need to work we need good cognition what does that require at a minimum our brains need to have good blood flow so we need to protect our circulation so foods that can actually help protect our circulation keep our circulation going are really helpful research has shown there's actually a natural chemical that's found in a lot of foods called ursolic acid that actually helps our blood vessel system stay healthy so we have better blood flow where do you get solic acid it comes in chestnuts it comes in Fruit peel which is found on dried fruits which are a healthy way to actually get a lot of dietary fiber which feeds our gut microbiome our healthy gut bacteria in our body and healthy gut bacteria text messages our brain and helps us release social hormones so we're happy to do the things and see the people that we happen to see and so this is sort of like a little bit of a contextual idea of some of the foods that we can eat and the reasons why in order to be able to have a good long healthy life I I think number one would be actually a good having a a brain working really well second one just tell you is you know we want to be able to move we want to actually you know you don't want to be wheelchair bound or paralyzed or or so weak we're unable to be independent or as independent as we possibly can so we need our muscles to be able to function properly now muscles are built and broken down on a daily basis which is why you know young kids are so active and teenagers are working out and you know why we actually try to encourage people to actually exercise is that you know use it or lose it is really absolutely true so we want to use it well in addition to just physically exercising we need to be able to actually build our muscles now how does our body build our muscles from the time we're born all the way until our Advanced ages use the stem cells now these are not the stem cells you would get at the strip mall injected into your knee you know or your for your tennis elbow or your shoulder these are stem cells we were born with and a lot of people don't know this but humans do regenerate we actually formed of stem cells when our mom's egg met our dad's sperm and we were just a ball of cells all stem cells and these stem cells that will want from your jaw and our face and our ears and our livers and our hearts and we have a bunch left over when we're born about 70 million leftover cells they're packed away kind of like on the shelves of Home Depot you know EXT cans of paint you can draw on them when you need to and these stem cells actually will participate in building our muscle over time so what are some of the foods that actually help us build help our stem cells come out so they can help to regenerate things well it turns out that extra virgin olive oil turns out to be really helpful for our stem cells it protects our stem cells as we age and not surprisingly in the blue zones those parts of the world where people live really to healthy ripe old ages over 100 for example centenarians they tend to eat olive oil extra virgin olive oil which by the way comes from a plant it's a plant-based healthy fat number two there's another fat that you should know about that's found associated with protein that's in seafood and that's omega-3 fatty acids Omega-3s also help our stem cells regenerate they prompt our body to stay renewed which is important for aging where do you get Omega-3s well besides salmon and Anchovies and mackerel and sardines you hear about that a lot it turns out many many many different kinds of Seafoods and even seaweeds actually edible seaweeds actually have omega-3 so one of the things that I write about in my new book Eat to beat your diet is leaning into that Seafood section of the grocery store which you know some people already like seafood but some people aren't familiar and I want to take people's apprehension away to say dive in there because there's a lot of great stuff that's a secret to longevity as well it turns out in many of the blue zones and in many places where people live to a ripe old age they eat reasonable amounts of seafood regularly and not surprisingly this omega-3 is found in there now I'm going to throw one last kind of delight and surprise that can help your stem cells which help to rebuild your brain and your heart and your muscles actually is dark chocolate turns out chocolate's a candy okay it's a confection but to make dark chocolate you have high amounts 70% 80% 90% cacao Cacao is actually from the sea pod the cacao plant and that's a plant-based food it turns out there's natural chemicals bioactives in cacao made in dark chocolate in high concentrations that help our stem cells come out and rebuild our muscles our circulation many other parts that need to be renewed and as we get older one of the things we want to do is we want to continuously be renewed rather than broken down these are some of the ways that we think about diet and Longevity those are some great tips and some great Foods as you were naming those Foods I was like yep definitely eat that yep definitely eat that and it just seems like it's pretty consistent too with the like the Mediterranean dietary pattern right would you say that that's pretty accurate absolutely and here's the thing that I think is really important to understand about the Mediterranean diet as you said that it's a pattern it's not a single recipe or a single commercial package the Mediterranean is not just Italy and Greece and Spain which people can pick out in two seconds but in fact it's made up of like 27 different countries that all surround the Mediterranean Sea and most people don't realize this but Tunisia and Israel Croatia are all Mediterranean countries and what that means that there's a really rich diversity of traditional foods that people have enjoyed so you know for people that say well you know I'm not really into Italian food or I'm not really I don't know wouldn't be in Italian food but you know some people are very picky with their food what I say is that if you want to look at Mediterranean pattern you have to appreciate this is more than 20 different countries that have something to offer for you and similarly Mediterranean is one pattern of healthy eating but the other pattern of healthy eating is in Asia because Asians live uh there's a long pattern of longevity it's traditional patterns lots of seafood lots of plant-based foods and here's the cool thing Doug is that the Mediterranean in Asia if you think about restaurant menus might look like there couldn't be more differences but then two different types of Cuisine but in fact the pattern of eating and the things that are in them could not be more connected because 2,000 years ago there was something called The Silk Road and it was a series of Dusty trails that linked China to the Mediterranean and the traders that did trade silk but many other things as well also exchang their ingredients and recipes and so when you want to think about healthy patterns of eating please do think about Mediterranean eating and realize that Mediterranean is much more than Italian food it's a lot of different foods but now I want you to actually open this up to a kaleidoscope of Cuisine that includes Asia and the interconnections between Mediterranean Asia and I actually in my new book I call this mediterasian because it really is something that is not new but thousands of years old old and now it's time for us to kind of really go back and tap that well of culinary genius that's always existed and the stuff tastes great too what myth around eating for a healthy heart most annoys you you know as somebody who studies blood vessels and circulation which is what the heart is all about the thing that really um irritates me is when people think that just simply working out whether it's jogging going to the gym lifting thing that that'll actually guarantee that you're going to be heart healthy in fact that's only a bit of the solution oh that's fascinating all right we're definitely going to talk some more about that will what are your three tips for living longer three tips number one get good quality sleep I'm a doctor I went through training I was deprived of sleep for years that subtracts years off of your life so get some good rest second eat healthy um and what that means is going to be different for every individual but bottom line is that listen to your body because your body knows what actually is not so good for you when you feel badly and there's a huge literature of studying what's actually um good for you mostly plant-based foods and we can talk more about that um and then the third thing really is to stay Physically Active that doesn't mean you have to jog swim run a marathon what it means that you have to actually move brilliant you know I think everybody here knows that their heart is really important right anyone for the last 100 years has been told about that I think most of us and and I'm included have never really thought about our blood vessels and I know that blood vessels have been the center of your research can you start Maybe by explaining why our blood vessels matter yeah well you know I'm a physician I'm a scientist I'm a vascular biologist which means I study blood vessels and the cardiovascular system and here's a little fact that most people don't know first of all when it comes to your heart which is about the size of your fist that's the best kind of surrogate measure of what it looks like in your chest this heart this beating muscle is connected to 60,000 miles of blood vessels that course throughout your body 60,000 miles 60,000 miles now if you were to pull out all the blood vessels in your body and line them up end to end you'd form a thread that would wrap around the earth twice now you can imagine how important blood vessels are when they're connected to the heart this way because your heart every beat every pump Jets out blood through these highways and byways that bring the blood the nourishment the oxygen you breathe all the growth factors to every cell in every organ of your body I've suddenly discovered that there's 60,000 miles of blood vessel inside me which is amazing wraps around the earth twice not something to try at home I guess um how does it link then from these blood vessels to actually impacting you know our heart health which I think is the thing we we we think about what what's going on and and how does that link yeah well you know I I'm sort of trying to give people a view that they may not have thought about right because most people think of the heart you go jogging you hear the ldb in the the background the the soundtrack of your heartbeating but here's something most people don't know is that when we were all in our mother's womb forming one of the first organs that we formed is it your brain is it your liver is it your bones it's actually your heart and your circulatory system and they all form pretty much at the same time and they form with these things called stem cells so imagine just dropping a group of marbles on the ground and just and they randomly kind of fall on the carpet they roll around and they don't look like anything those are your stum cells that say day five day seven after conception when dad's sperm met mom's egg over the course of the next weeks those marbles coales together and they begin to organize themselves to form these channels they call them first Lakes blood Lakes before they form tributaries before they form streams and that's basically at the end of the day they're left with one additional area which is the heart that is special because it actually has muscles special muscles that will actually pump and its own electrical system and so basically when you think about how your heart and your blood vessels are actually connected together they were formed together at the very beginning all right so what happens to your heart will impact your blood vessels your circulation and therefore your organs and what happens to your blood vessels actually impacts the heart as well so if you have very stiff blood vessels now blood vessels are actually very elastic so basically when your heart pumps they will stretch to accommodate the blood all right um because a normal capillary the smallest blood vessel at the very like just getting into your organs to feed your cells that's the thinness of a human hair that's a human capillary now to Jet blood through that in fact that that diameter of that blood vessels is smaller than a single blood cell so even for a a healthy blood cell to get through that end Channel it has to stretch to allow things through oh wow so everything I think about this like these tiny little elastic things that are opening and closing to squeeze through like literally my blood cells that's right without my blood cells my organs are in trouble is that right without your blood cells pumping through delivering those oxygen carrying oxygen rich red blood cells very quickly and I'm talking about within seconds your organs start feeling starved think about getting choked you can't breathe all right and then soon it turns blue just like You' be blue in the face and shortly after that your organs stop functioning properly and when they actually stop functioning properly um they start to uh malfunction the ultimate malfunction whether it's in the liver whether it's your kidney whether it's your brain I mean the ultimate brain malfunction is you have a stroke and all and this by the way everything I'm talking about in your organs also can happen to your heart so when that when there's a malfunction of your heart because it's not getting enough blood flow we can also happen the heart has its own circulation which is pretty amazing um not surprising but amazing when the heart's own circulation gets clogged or too stiff and it blocks blood flow then you have a heart attack and so the things that we hear about heart attack stroke cardiovascular disease these are all problems of that giant system that 60,000 M system that formed um was one of the first organs to form in your mom's womb and so I need this stretchiness in order to deliver down these capillaries and I think we've all maybe heard a little bit about this idea of it being blocked how does that is that the same as not being stretchy or is that actually something different will right well think about this um so think about a a big sock that you put in your foot through right so the sock has to stretch like the stock you pull out of the St out of a drawer is actually pretty thin it looks too thin for your leg to go through but because it's stretchy you can actually put your foot and then your ankle all the way through it right yep I'm familiar I fought with my daughter this morning to do exactly that as I seem to end up doing many mornings because it turns out that it's a lot easier to put your foot through the sock when the other person is helping rather than pulling it in the other direction so right I understand the analogy now when that sock is no longer stretchy it's stiff imagine spraying concrete around that sock or maybe even pouring concrete into the sock okay and and now try to put your foot through it it's not going to go through very easily right it's stiff there's no stretchiness and that's actually what happens as we naturally get older and particularly when we're eating what is the so-called Western diet now that's we can talk about that in more detail but we eat a diet that's not so good for our circulation what happens is that a blood vessel let me just kind of give you a little more detail about the stretch the reason a blood vessel can stretch has to do with how it's designed um a blood vessel has got different um uh uh aspects of its wall cut a blood vessel in half and look at its cross-section and you'll see there's a thin lining on the outside there's a little muscle on the out beyond that so the muscle can allow it to stretch and on the inside there's a lining of cells very special cells called endothelial cells Endo because they're on the inside endothelial cells these are the liner cells of a blood vessel so think about Saran Wrap that's how thin it is okay aligning the inside of your blood vessel cling film for those of us in in the UK yep clear film that by the way so basically that's the blood vessel the muscle helps it stretch the wall helps it stretch the the the um the the clear sheet on the inside that is a special layer that layer is slippery it's like the surface of an ice skating rink that's been polished and buffed before the first skaters got get on it and the reason that endothelial slippery layer is so important is because blood cells slide right along it they don't stick got it so I'm sort of thinking now bet it's like you're in a tunnel but all the walls are covered in like a bit like Teflon I guess on my pans or something right like something very non-stick is that a way to right to think about this well we'll have to talk about the Teflon in your pan from a healthy eating perspective but but but yes that's exactly what it is um and I and I and I use the idea of an ice skating rink because many people have you know um spent a winter holiday looking I could be out doors it could be insort as a as a skating rink or just think about the Olympics right um so when the ice is fresh and ready for the first the day's first skaters it is it is slick it is smooth and everything just starts at one end and goes all the way to the other ends yeah take off your sweater and throw it on the ice and it will go all the way across the rink right now as long as that lining is perfectly smooth everything will Glide right along now what happens when you actually um smoke a cigarette okay uh the the the nicotine the chemicals the harsh chemicals it damages that Teflon layer it damages that liner that transparent liner uh it going back to the ice skating rink analogy it would be like if you took um a rake and you just raked the ice and scuffed it up now try to throw a sweater on it it's not it's just going to stick right there it won't slide and so that roughening up of the inner lining can actually make blood cells clut stick and form a clut that is the beginning of the end when I say the beginning of the end that starts to narrow the blood vessel the blood vessel starts to get stiffer you don't actually have that stretchiness um plaques fat can actually build on the inside of the wall and what is a plaque will a plaque is a thickening you know like a plaque on your teeth is anything any kind of a thing that builds up on your teeth right so a plaque in a blood vessel is similar to what you would find in your teeth but it's on the inside layer and it what it does is it makes it stickier it makes it narrower it makes it stiffer all the things you don't want in a healthy blood vessel that makes sense and I can see if you're trying to deliver if I'm trying to deliver anything through this and it's starting to get more and more constricted I mean it doesn't it's sort of obvious to a Layman right it doesn't sound good if I trying to push something through and the pipe is getting more and more more furred up so is there a is there you know I have a toothbrush for my teeth right for for this situation with plaque is there is there a is there a toothbrush in this situation or is this a sort of oneway Direction This is just going to get worse and worse as we get older and we we we fur up these um blood vessels well well this is actually the most exciting thing when I went to medical school we thought it was a one-way Street meaning once you start narrowing and stiff ing the blood vessels the only way you could do it we used to think about it like a clogged toilet right like we've all experienced that toilet is supposed to flush go all of a sudden it's not flushing anymore it backs up terrible what do you have to do you have have to like PL plunge it call the plumber or you have to snake something down it to clear it right and so that's what we I was taught when I was in medical school you got to call the the heart plumber the cardiologist the Interventional cardiologist who basically will stick a rotor rotter which is like a coil in your uh in your groin snake it up through the blood vessels and you're growing into the blood vessels in your heart and literally rotor it like basically drill out that clog to clear the toilet so it is a bit like brushing your teeth uh fancy technology but exactly well and and then of course it would clog back up and so what they then invented in the medical world are Sten which are literally little Teflon or metal coated stance that would strut the um the uh the blood vessel open right so sort of like a like a thin like think about Mission Impossible you get this little thin thing you put it into the blood vessel and then boom it opens up and now it's actually stenting open forcing open the blood vessel now that sounds good because you solve the immediate problem of the lack of blood flow but actually gets what that actually also damages the natural elasticity stretchiness of the blood vessels now You' got basically an an iron tube stuck inside your blood vessels that's not normal and that's not good so then we developed statins which are drugs aimed at actually um lowering the amount of stuff that could clog fatty deposits that can clog uh the plaque um on the walls statins actually work pretty well they work by metabolically uh lowering the amount of cholesterol and other lipids fatty things um that float around your blood um if you've ever cooked bacon you know that you know after the the raw bacon starts frying up and the wonderful bacony smell is in the air and you take the bacon out you know that you're left with a pan of a pan of Grease right now you're going off eating your brunch or what have you you come back to the pan after breakfast and what do you actually have you've got this congealed mess imagine that congealed white creamy thick stuff the bacon grease imagine that is actually sosing through your blood doesn't sound good right like nobody's G to suggest that this sounds like a good thing to be going on inside you no and that's what statson were designed to do is to sort of try to cut through that grease like a detergent and lower the levels in your blood sounds like a good idea but here's the problem statins um which are capable of actually preventing the buildup to some extent have a lot of side effects actually most there's I mean it's a billion dooll Blockbuster area Pharmaceuticals and many many people are on them but you know statens can damage your muscles can damage your kidney can damage your liver there's all kinds of things every drug has an effect and the potential for a side effect or an unwanted effect so not particularly a a great solution and frankly not a not a you know people don't shouldn't take medicines I look I'm a doctor I was trained to write prescriptions but my own practice my own mindset of how to help a patient is really to try if you have are forced to give somebody a prescription my goal has always been to figure out from the beginning when you're going to take the person off the prescription so they no longer need the drug now you need to find a different solution so this is different than putting writing a prescription and putting somebody on a drug for the rest of their life right like how many of us know people like that and or even doctors who actually think that way my view is that medicines can be lifesaving but if you put somebody on a medicine the goal ideally is to figure out how you're going from the beginning when you're going to take them off it so now research actually has then discovered that there are foods and lifestyle issues that can actually reverse all the things that damage the elasticity the the flow uh uh that can block your circulation I mean we started at the very beginning right we just started saying drop those marbles their stem cell they haven't formed and then they form and they work perfectly when you're a baby and over the course of your life over age during aging and over the course of maybe un un less than uh salutory dietary habits you're eating foods that are not so good for your circulation you get the clogging gets a cigarette smoke damages that smooth ice and now it's sticky all right um you know we can can we avoid stance I think we can can we use drugs yeah I think we can but can we use diet and lifestyle to reverse that clogging that prevent and reverse that is actually what's remarkable because scientists now discovered it's possible to not rely on the drugs or the hardware that I was taught we that doctor the medical community has to use about the the impact of the gut microbiome and how that can be tied to body flat and specific to that one particular uh organism that is starting to we're starting to hear more about acrania can we talk about the interplay between the gut microbiome and our metabolism and this very important uh you know organism that many people may be unfamiliar with okay everyone's probably by now heard about gut health and thought about gut health if this has been something that you've heard about ask a friend or family they'll start rambling on about everything about it okay here's the thing gut health in scientific terms and medical terms relates to um relates a lot refers to you know our gut microbiome and our gut microbiome is really the bacteria that is mostly in the PO last part of our gut it's an area in the colum called the seeum um and although not all of our body's healthy bacteria is there a lot of it is what's a lot 39 trillion bacteria that's a lot of bacteria our body is only made of 40 trillion cells so we're about 50/50 bacteria and 50 the other 50% is human all right and so what we realized is and again I I'll I'll confess this as a as a Bonafide MD who went through medical school is that when I went to medical school and you probably had the same thing Cynthia is that I was taught that bacteria are bad must kill bacteria and now must memorize all the bacteria you must kill with prescription antibiotics that are necessary in order to stay clean and healthy Well turns out that's all like a little bit Mis emphasized because most bacteria that we encounter throughout our lives are good bacteria almost all of them are good bacteria um and and we do encounter a few bad guys you know I mean think about it it's like saying that the way that medical that the medical community was trained is like everyone's a terrorist must kill terrorists but in fact actually most people are good guys most people are ordinary peac Loving Citizens and yeah there's a few you know Bad actors out there we do want to make sure that we're keeping an eye out for them right so it's really what's amazing to me is how modern science is teaching us to upend a lot of the traditional teachings that the medical community actually has been saddled with over the decades um so gut microbiome are healthy bacteria living in our gut there's a lot of different bacteria not only bacteria by the way there's always also viruses there's also fi there's also another type of small um organism that most people don't talk about don't even know about called ARA um that's another kind of member of the of the gut Garden that's out there but let's not go there right now I'll tell you about the bacteria um uh we are just beginning to understand the importance of the gut microbiome and we do know that um the bacteria in our gut talks through um uh the wall of our intestines because they're living inside our intestine they talk to our immune system and they talk to our immune system right through the wall of the bacteria it's like they they're I would say it's like college roommates um in a dorm with really thin walls and basically the bacteria which is one roommate pounding on the wall to to the roommate basically saying hey what kind of pizza do you want all right and then the roommate can hear on the other side and shouts back i' like mushroom or or or olives and basically our bacteria and our immune system talk to each other that way and good healthy gut give good instructions to our immune system and this is really kind of a an eye opener to realize that our immune system is so tightly connected and when our gut bacteria is not healthy um not only is our immunity our defenses down for immunity but our inflammation which is another part of our immune system goes up and the gut bacteria not only influences our immune system but also influences our metabolism it influences our um our lipid cholesterol and levels uh in our body it INF the inflammation actually is really important to control because if we've got extra body fat basically we've got a for we've got um uh we've got actually um a smoldering fire burning in our body okay and it's our healthy gut bacteria that puts out that smoldering fire like we to put out that fir fire to prevent it from become a wildfire we need good healthy gut bacteria and you know most people have not until recently paid attention to their gut so and we're all we've all been through this before you know like when when you're feeling okay and then one week you're not feeling okay you're gassy you're crampy you're not regular or you're having loose stools and you're just not feeling that good you're not talking about it to people mostly okay that means that you don't have good gut health and most likely there's something going on with your gut bacteria we are just beginning to actually understand that we got to pay attention to that now a lot of people out there say that they've got a solution do my stool test and get my biotic and what I will tell you is that we don't understand enough about it yet to come up with a definitive solution however there are certain bacteria that are very very interesting one of them is called acrania mcop acrania AK k k r m an c i s i a um that's the first name the last name the genus of species is muop M muop because it actually likes to live in the mucus of your gut now I learned about acromania mucil not in a metabolism setting uh not in a diabetes or an obesity setting but actually in a cancer setting because I I do cancer research few years ago I was with a colleague of mine Dr luron cogle who discovered in cancer patients getting immune therapy treatments that actually activate our body's own immune system to fight the cancer that the people who responded well whose immune system could be coached by the treatment to go out and destroy their own cancer people who survived actually had acromania and the people who unfortunately didn't respond meaning their immune system did not respond Wen couldn't be coached by um the the immunotherapy lacked this one particular gut bacteria AC acromium copil so that's really interesting one bacteria could make the difference between whether you lived or died as a cancer patient with a particular kind of treatment to me like my my radar went up right away like oh my gosh we got to figure out more about this and the more we actually discovered about this so what um laurance zoku did she took out the acromania from these Sur these responders cancer patient survivors and took them to the lab and gave them to lab animals that were developing cancer and gave those lab animals immunotherapy and so they would respond if they had the acrania from the patient then she gave them antibiotics to wipe out the acromania and and the cancer grew right back and killed the animals so just like the patient and so this was you know this was I think 201 2017 and now the research has continued to evolve now we're finding that it's not just cancer okay uh which is not about cancer it's really about the immune system our own health defenses but another defense is really about able to tame our adapost tissue and our metabolism people with good metabolisms have more acromania people with and and and this is actually a really strange observation so I'm a scientist so you know one of the important things about scientists is you can tell somebody's a real scientist when they tell you they don't know something all right so here's what we don't know but what we observed people who are suffering from obesity actually have hardly any or no acromania in their gut people that are lean with good metabolisms actually have acromania so this is a observation that we need to pay attention to how come one group doesn't have acroman is it cause or an effect what is acromania doing well it looks like AC acromania may be controlling the lipids might be influencing inflammation you know really really being helpful and so then the question is how do you grow your own acromania okay well it turns out that if that there are certain foods containing polyphenols like pomegranate juice that contain elianin is a bioactive that that doesn't acts directly on the bacteria the acromania it prompts your gut to secrete more mucus there's more soil for the acrian to grow so it's basically like a gardener saying how do I put more fertilizer for my flower bed to bloom my annuals to bloom so pomegranate juice conquered conquered grape juice cranberry juice have all been studyed they all have this lanin more mucus the more mucus there is the better the acromania grows and I can tell you I had a patient I once was treating who was had cancer she um was about to get an immunotherapy uh for for a cancer multiple Myoma and and I I told the oncologist hold off for a second because let's test her stool to see if she have acromania this is as a result of my knowing you know my work my my knowing about La Cal's work and so we tested her stool she had zero acromania why because her kids had had bronchitis it went right through the house she had gotten some antibiotics from you know a walk-in clinic uh and and um uh she had no acromania so we I said wait let's let's grow some back so we gave her pomegranate juice we try to really give her some fermented foods to really make her gut health better um we need more mucus we needed more gut health more probiotics some prebiotics probiotics then we tested her again a few weeks later and she had six times above the population General population's worth of acromania so if you're missing it I'm telling you diet can actually grow it back which is a wonderful thing and when we actually gave her the the the therapy she um actually responded completely like one of the best responders ever seen in history so I'm telling you this this is not food versus medicine in this case it's food and medicine or food before medicine and it's really about the body and the wonderful things that we can do to feed our body's Health defenses feed our body's metabolism it's all stuff that's inside us well it makes so much sense and I love that it's tangible it's not an unusual thing that people have to to go purchase to be able to support their gut microbiome now I want to be respectful of your time but I would love to kind of focus in on some of your favorite foods you do a beautiful job in the book really talking about specific Foods um and compounds that can be very very beneficial for helping support metabolism and then briefly touch on the mediterrasian uh you know kind of concept which is so aligned I grew up with an Italian mother and you know food was savored and it took you took long meals there was no rushing around but let's touch on those things and the other piece that I want to compliment you on is that I read so many books for the podcast and sometimes there are intangible things but you do such a nice job of describing the food item and exactly the amount that you need to consume so you're not wandering around saying are you talking about a cup of something or is it a tablespoon you're very specific about your recommendations yeah no well thank you for your your your kind words look um I'm somebody who really um grew up like you um uh around really delicious food um I grew up in uh the city of Pittsburgh Pennsylvania where there's a lot of ethnic communities and I went to these folk festivals or we got to sample a lot of things look we all come from different places um we all have our own origin stories in terms of uh every culture in the world has its own food story um and and food traditions and I and I love that I I really respect that and one of the things of my research you know I talk about that in our food ingredients there are these compounds that might be tongue twisters for people to pronounce lopine chlorogenic acid zanthin you know B crypto xanthin I could go on and on you know Alice and hydroxy tyol they're all in the book if you want to read about them uh but what's important is that they're all found in our Foods they're found in things like tomatoes and apples and pears and garlic and and scallions and garlic Scapes and um and lots of seafood as well including the omega-3 fatty acids and and what I try to do is sort of take away some of the mystery look Mother Nature is very clever and incredible she has gifted us with so many healthy natural chemicals that activate our body self defenses that help us tame our metabolism and allow and fight body fat uh uh so they're in there so what are those what are some of the favorite foods um well I in my book I wanted to do something that I know a lot of diet books don't and I wanted to take people on a tour of the plain old grocery store the way that I go through it and point out take them on a tour to point out the things that I see as you go around go to the produce section which is usually the first section what am I seeing I'm seeing Tomatoes I'm seeing brassa vegetables I'm seeing the broccoli the kale I'm seeing the bok choy the Baby Bach Choy then I'm seeing the mushrooms and I'm seeing the red onions and I talk about all these things and try to provide a little little bit of you know underneath the hood give a little clue into what how do we know it's good for you and one of the things that I really do um that you just pointed out Cynthia is I point out the human evidence what is the clinical study the lab stud is interesting especially the scientists but the human study is what people care about and in the human study you always have a dose an amount a frequency just like any medicine which is food is medicine so I I publish that around so every food that I talk about or almost every food I should talk about um the doses so um you know what what's interesting is like paars pears actually have been able to reduce waste circumf how does it do it by shrinking the visceral fat that you know the the harmful fat the gut fat it's kind of like a baseball glove that's like packing or squeezing your organs and in a study that was done to show that you can lose like two belt two inches around your waist circumference by eating pears how much do they give two mediumsized pairs um before lunch for 12 weeks and what they even tell you what kind of pairs okay there were bartler Pairs and alju pairs hey these are the things that you see in the grocery store so I literally take people to the produce section then I go to the seafood section um because this is a whole other podcast probably like things that people are not comfortable with fish and seafood you know like I didn't goow around fish I don't like fish look there are so many incredible delicious amazing Seafoods to enjoy and I'll come back to that with mediteran that I actually spent a whole chapter diving into things that you'd recognize and a lot of seafood I'm willing to bet you don't recognized like the um Mitten crab or the um the mantis shrimp these are things that you know are out there I really want to punch through the brick wall um and show you that there's a there is a lot of stuff that you haven't discovered yet when to demystify that and tell you the dose of that of that to eat as well and then of course the Forbidden middle aisle I wanted to people say you know what it's time to grow up and get out of this like you know this uh this elimination thing don't even go to the middle aisle wrong I call the my chapter's in in the book e to be your D is called treasure hunt go into the middle aisle with your bucket your cart to a hunt for the treasures that help your metabolism like navy beans like lenos like extra virgin olive oil like apple cider vinegar um there like dried prun like dried mushrooms and Chili Pepper powder and turmeric I just all these things that you know I'm trying to let people know that this is every day anybody can do this this is not mystery and this isn't about elimination this is actually encouragement to Dive Right In and find the thing that fits you so what fits me I always get asked this question Dr Lee you know you write about food and health you're a food is medicine researcher how what diet are you on and I tell people I'm not on a diet but I do have a way that I eat in my way I call mediterasian I'm Asian I grew up in a Chinese family I had lots of Asian food um I also spent a gap year in the Mediterranean before I went to medical school I I lived in Italy I lived in Greece um and then after that I went to China and I and what I was interested in doing on those Gap years is to study food culture and health and so to me what's really wonderful is that there is a beautiful way that these natural ingredients whether you know the chemical names or not have been incorporated into into recipes and they're easy to find on the internet um they're many of them are traditional your grandmother and her grandmother were making these Foods okay natural fresh local seasonal all that stuff that you hear about that sounds trendy and cooking them and sharing them and eating them that contain fiber they may be fermented they have these polyphenols in ways that everyone can enjoy and Savor without wolfing your food down and you know I mean if you went to a traditional um uh household uh eating like in Italy or Greece and and and somebody watched you w wolfing food done and hit you with a spoon because you're not supposed to eat that way right like and and I think that this is really what I talk about mediteran is going back to the basics becoming reconnected with the traditions of some of the healthiest cuisines in the world and and and appreciating the fact that these are delicious foods that you can really love your food to love your metabolism and to love your health all at the same time that's what my book is about hi there if you enjoyed watching this video I know you'll love the next one stay here and check it out and I'll see you there