Kind: captions Language: en it it's quite a radical statement you just made instead of chasing disease you're trying to think about the common denominators of health and it's not something we learned about in medical school how many of us took that class creating Health 101 I mean it didn't exist in class right and and so your your framework is is a radically different one it is so unusual in medicine how did you actually sort of have that Insight because that's a that's a pretty big shift from like wait a minute I don't want to focus on treating all these 70 diseases I want to find out the common things that are underlying them that connect the dots and pull everything together to allow us to actually uh create health and as a side effect the diseases either get better improve or maybe go away entirely well look most of us actually don't think too much about our health when we're going around you know getting as we're younger growing up going leading careers Etc starting families but in fact you think about health when you lose it right so that's basically what we see as doctors when we see our patients they're concerned when they've lost their health and and it seems to me that if we can help more people stay healthy but really use science not guesswork not conjecture not um soap boxing and and I think this is where science comes in uh you and I have talked about this before there is good hard science that can help us understand the body and yes we were not taught this in medical school but we should be because the science of health is really the future of medicine it's it's it's really powerful and that's what functional medicine is and coming from your perspective you know we've come out of from the clinical perspective which is you know we're seeing these common things we we try to create Health by changing the diet by optimizing the microbiome by improving the immune system by improving your energy and your mitochondria helping you detoxify balancing your hormones you know dealing with your lifestyle factors these are the ways in which we create health and it's it's pretty rudimentary I would say I mean functional medicine is is awesome clinically but we're just at the infancy stages of really understanding this and you come at it from the deep science point of view and and that and you come to the same conclusion which is pretty awesome so let's talk about uh some powerful new drugs uh that have been discovered that can affect angiogenesis and that actually may be able to reverse many diseases now these drugs are are are things maybe people have heard about like kakin genestin ratol lycopene osip pentanoic acid glucosinolates isoionic tannins curcumin met quinone beta kryo zanthin brassinin camarin or Organo suur Al Al disulfide this are amazing drugs and U for those of you who don't understand what I just said what I was talking about was green tea and soy and red wine and grapes and tomatoes and fish oil and broccoli and oranges and berries and and pomegranate and curcumin and green leafy vegetables and papaya and Chinese cabbage and AR arti jokes and garlic right these are the new drugs and you write about this and there's a beautiful article you wrote it was in Journal of oncology called tumor angiogenesis as a target for dietary cancer prevention now most people are going to have trouble reading it I I certainly was was dense for me but what you did was you mapped out the Deep science around the power of all these different compounds and foods to help reverse disease so as a scientist you know what's nice about science is that it is um truth and we follow truth wherever it goes and basically the route that I took is um there's a lot of research that leads to the discovery of new um drugs by the pharmaceutical Biotech Industry I've been there done that still involved with it actually and it's because we have more sick people that need better treatment so that's valuable by itself it's not either or it's not either or and you know I'm certainly not one of those doctors that have sort of rejected Western biom medicine like it's very important when you're sick to help save lives on the other hand what I realize is that there's a missing opportunity and and that opportunity is what everybody sort of intuitively knows which is that the things that we put into our body can affect our body and they affect our cell and food as medicine is really not a New Concept it's an old concept and if you go other cultures whether you're in Europe or you Asia indigenous uh peoples uh from all around the world they looked at food as part of their health keeping scorecard and they viewed food as a precious substance not you know they didn't just eat to survive they ate because they were doing something good for themselves we've lost a little bit of that and the research behind it actually resurfaces this in a new way that I think that we can all get behind which is not in fact it's not really just about the food it's about how our body responds to the food how does our body protect its health and that's what the health defense systems are all about it's true I remember uh traveling once in Hong Kong and I went out to dinner with this guy I think he was part of maril linch I gave a talk and we had this extraordinary meal and everything in the meal was medicine intentionally medicine and I wrote a article about it called eating your medicine food is pharmacology and then I went through all the dishes we had and I went through the research and I was like well gko nuts do this and you know this thing does that and it was a said amazing kind of uh experience because I realize that in this culture we don't think of food that way and yet that's that's foundational for creating Health well that's why I wrote e to be disease uh is that you know while I do explain the science behind things I actually lay out more than 200 different foods that are actually some of them are real crowd-pleasers or the things that we actually know that are supported by science and then figure out how can you incorporate that because in fact um it becomes natural to pick the things that are good for you it's that's something we've L that we can bring put back into our everyday lives and for me when I uh go out to eat or when I prepare a meal that's what I'm doing I'm actually assembling things that I know are good for me absolutely that's why this show is called The Doctor's Pharmacy with an f f a r m a c y because that's where you get your drugs I go to the drugstore which is the grocery store and that's where I find all the drugs and I literally don't know as much as you perhaps about this because even though I've been doing for a long time but I look at all the vegetables and all the foods now I I didn't know Razer clams we're going to get into that are so beneficial I don't know exactly know why but I love them but you can find out what are the foods that have various components that can activate Health right and how do you eat more of those things well I think it makes it it's about having knowledge uh and then making it second nature right so when we heat up something on a stove we know it's going to be hot we don't burn ourselves so we actually avoid certain behaviors when we go onto the sun we know to put on sunscreen it becomes second nature I think think food as medicine is something that can become second nature you have to be exposed to the basic information and you know the science is important because that's what makes it real but at the end of the day is you know this is something that school teachers should be teaching kids that at coaches should be teaching athletes that doctors should be um telling patients and so and I think family members should be uh sharing among themselves this is the type of conversation that should be having at every holiday meal uh in every schoolyard and and I I think that it's not so foreign it's informed by science and we can all do it it's true no the other thing I I heard you say was at this conference was you showed a slide around immunotherapy for those you know what immunotherapy is is essentially a way to um get cancer by activating your immune system rather than giving a poison or cutting it out or burning it out right you literally give something that's going to help your immune system get into gear and be like Pac-Man and eat up the cancer uh and you showed a slide and and who would have thought of this but you showed a slide that people who respond to the KE this immunotherapy and and these can erase cancers actually have a certain type of bacteria in their microbiome in their gut that makes them respond to the to this immunotherapy whereas those who don't actually die and and this bacteria is called acrania it's one of the you know thousands and thousands of species of bugs in your gut and you shared a story if I may about your mom yeah who had basically metastatic IND demetrial cancer which uh was treated with immunotherapy and was successful but you added certain things to the treatment to to make sure that her acromania were good like pomegranate and cranberry and these polyphenols which come from food that seem to be powerful Growers of these great bugs in your gut so how do we how do we sort of begin to integrate these ideas into how we treat these diseases are we giving everybody like a a smoothie with all these things in it and helping them with their immunotherapy yeah well let's take a step back to say first of all uh our bodies are working hard every single day from the time we're born to our last breath to defend our health and these defense systems and I've identified five of them in uh my book uh is and Genesis stem cells our microbiome our ability for our DNA to protect our body protect itself and our body and our health and our immunity and all these defense systems work together in concert they're like our security force in our body they're patrolling they're watching out they're making sure everybody's safe inside and everything is functioning smoothly and when you have a disease like cancer for example and it's not just cancer it's heart disease it's diabetes it's Alzheimer's it's obesity um but for specifically for cancer it's really you know um a few bad guys snuck in and they figured out how to get around the security Force you know it's sort of like you know TSA slip let somebody slip by and now we have to try to chase it so in the old days for cancer what we used to do is just say well let's you know um take a drug- like chemotherapy and wipe it out and you know that that's a blunt instrument approach by trying to take something poison to kill something that you want to kill by the way the rest of you gets poison too well that's right and so basically it's it's a toxic approach to uh uh uh to something that we don't really it's one bad actor but we don't want to poison the entire uh body we've now changed our minds about this and this is really what's making the impossible possible we' realized that it's not about drugs killing cancer it's about our bodies taking care of itself and wiping out those cancers so immunotherapy which is what you were just bringing up is an entirely new approach of enhancing our own body's defenses we don't use drugs to kill the cancer we allow our bodies we give medicines that allow our bodies to kill kill the cancer so immune systems can find the cancer and reverse the disease back to health that's what we've always been dreaming of and it's here but here's a problem only about 20% of people actually have this incredible response to immunotherapy sometimes a few a little fewer sometimes a little bit more but the response when it happens is exactly what we want dramatic right your Mom it just my mom metastatic cancer and in 30 days she had no cancer okay and never had chemotherapy what about what makes the difference between somebody who responds like that and who doesn't respond like that right that's a that's one of the Mysteries out there and this is exactly where we need to consider more than the typical lab tests that doctors run we need to think more holistically and one of the things we know is that our microbiome our healthy gut bacteria communicates talks to our immune system and it and we need our gut bacteria to help coach our immune system to do the right thing including getting cancer so a study done by a colleague of mine Dr luron zal uh she's in Paris she's a imuno immunologist who uh works with cancer patients she looked at 249 cancer patients who were receiving immune therapies and separated them into people who responded versus people who did not respond this by the way was published in the Journal of science which is one of the most prestigious yeah journals and what she found was that the difference between people who responded and didn't respond was one bacteria unbelievable acrania right so well isn't that easy you can just maybe take some probiotics with acrania except that you can't no there's no acromania probiotic but you can feed them but you can feed it and you can actually change your gut to make your body grow acromania and the way to do this is the food as medicine solution so turns out that pomegranates and cranberries actually have elit tannins um but pomegranates especially and that natural chemical in pomegranate juice and what's been shown is that just 1 8 O cup of real pomegranate juice not the flavored stuff but the real stuff actually over the course of a week or two will actually help change the inside of our guts so that that bacteria likes to grow that bacteria grows in the lining of the gut talks of the immune system and that makes the cancer immunotherapy work better yeah and then then there's other things too like like you said cranberries and and green tea many things can actually feed our microbiome right so plant-based Foods you know I think it's completely accepted now it's not challenged that plant-based nutrition is actually U the healthy approach to life I mean it's kind of eating more plants e more plants right but it's not just we're not just feeding ourselves we're feeding our bacteria yeah right so we're feeding the you know 37 trillion bacteria in our bodies and after we extract all the stuff that we need on The Human Side we're leaving you know the the leftovers for the bacteria and this is the fibers this is the bioactives and what's amazing is our bacteria can take some of this fiber and they digest it so it's kind of like giving a sculptor a block of wood and say do something with it so the bacteria our gut microbiome takes that block of wood and starts making sculptures there's like these things called short chain fatty acids or scaas that our microbiome make and it turns out that these short chain fatty acids these little tiny particles that they make from our food that that we feed them they're like the fats that fuel the gut lining help they do that they're anti-inflammatory they boost our immune system they help regulate our blood sugar they lower our cholesterol help cancer risk they and and they also suppress cancer risk and they um prevent blood vessels from growing into cancer as well all tied together and this is you know at at the end of the day why we need to take our food seriously yeah