Transcript
4rsvftouNRg • Let Food Be Thy Medicine: How To Drastically Heal & Prevent Disease | Dr. William Li
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Kind: captions Language: en how many of you have heard of the phrase food is medicine that's almost all of you and how many of you actually understand it because I know in this room there are Physicians who actually understand medicine but I don't see too many Physicians who understand food what I'm going to try to do is to bring you up to speed on how the Two Worlds of of nutrition and Medicine are starting to collide and give you a glimpse at the future of what food as medicine will really be like before I do that though I want to actually just um bring us all back to the old man himself hypocrates who uh lived in a time when people didn't eat they ate Fresh Foods there were no processed foods that we Ultra processed foods uh so to speak and he's the one that actually coed the term uh let food be thy medicine but back then it was really serious because they were um they were actually um uh medicating to themselves going forward and not actually trying to treat disease that had already left the barn so where do we take uh you know 2,000 years of wisdom and move it into the future before we go to the Future let's look at the present day right so uh everybody knows that this is the unfortunate scenario uh as was described expertly by my colleagues uh Dari mozafarian who's the dean of the tus nutrition school and uh and Dan Glickman who's a former secretary of agriculture and the idea really is that our food is really compromising our Health Care system in the United States about a half a million deaths uh worldwide about 11 million uh deaths a year attributed to poor diet and this is actually the study that they cited from jamama showing that the state of the US uh of Health in the US over the course of 25 years if you take a look at all those um disease entities that are in small type on the right hand side and look at the number one risk for mortality it's dietary risks accounting for for uh neoplasms cancer cardiovascular disease and diabetes right so these are the chronic diseases that actually ail our system our Health Care system that we're trying to figure out a way as we've been talking about over the last few years how to do early detection how to do monitoring how to actually do the appropriate types of feedback so let's dive a little bit further into dietary risk to understand what that is because most of us think of dietary risks as foods that we should cut out of our lives right human nature abhor deprivation so we don't really want to cut things out of our life in fact if I were to tell you something to remove from your life you might actually at some point after I told you that think about adding it sneaking it in just so that you can actually uh try that now what are the things that we know about dietary risk we know that we're not eating enough nuts and seeds fruits and vegetables uh low and omega-3 fatty acids and we're eating too many processed foods like red meat and processed meats and of course uh sugar sweetened beverages but that doesn't mean that this is a solution to health um the solution is really coming out of economic drivers so this is about $2 and half trillion dollars of Burden that um is attributed to some of these dietary risks diet isn't the full cause to these there's lots of other uh things we've talked about epigenetics genetic uh factors there's other lifestyle issues um uh stress social issues that actually are uh determinants of health and disease as well but I do think that we have to start here to take a look at what we can actually do about it now we are also not only interested in um our persons and our Comm our families and our communities we're also interested in the planet and in January of this year the E Lancet commission which is an International Coalition uh made a released a statement a study that said basically in order to create meet sustainability goals by 2050 we have to have the amount of red meat and sugar that we eat and we have to double the amount of fruits and nuts and vegetables in order to be good not only for the person but also for the planet and this kind of just raised a whole other set of issues that in some ways are controversial but also helped to bring the focus of nutrition and Food and Health into Clarity you got economics you've got policy Global policy you've got sustainability so it's not just no longer about the person going up on the podium talking about a vegan diet we're really talking about something that has true economic value and a driver uh for opportunity as well now different States now actually have food as medicine programs now even though most of us here said well we're not really sure what that means I can tell you that starting to be legislated uh even insurance companies actually are beginning to talk about you know cancer protection in a bag and so the vernacular of food is medicine is now actually starting to reach um uh the public and corporations and it's also on Capitol Hill there was a bipartisan announcement of the formation of a food as medicine working group within the hunger caucus that is now actually um uh uh meeting to talk about this issue as well and then finally even the Vatican has gotten involved this is actually from a conference that I um gave an address at talking about uh uh using diet to mobilize our defenses against the disease and a degrading environment and so you can kind of see this is no longer really a bunch of extremists talking about vegan diets and at the salad bar we're really talking about a kind of a global aw Awakening and that's really what I want to share with you is that this Global Awakening is going to drive things into the future so what does that mean does that mean that we all just go to the veggie counter at the Whole Foods to be able to get um a plate full of healthy foods this is actually what most people think about as food as medicine let's let's get rid of all the bad stuff let's pile up a bowl and let's go ahead and Munch down but if you think about it this is a solution but it's not the whole solution and it can't be because there's a lot of science that is still unnown that still needs to be unraveled about what it is about food I mean are there superfoods is there a Super Supplement probably not there are no super drugs either what we know is that the body actually is very complex and actually uh uh responds to Foods on an individual as well as a systemic level in ways that we barely understand so where are the good ideas where is the uh scientific evidence the basis for actually Innovation going into the future coming from I'm actually not going to talk about um uh uh the uh uh the plant uh plant-based food movement because there's plenty of other people out there that are very well qualified to talk about that I'm actually not going to talk about sustaining sustainable farming or regenerative agriculture there are other people that are talking about that important topic as well but I will actually tell you that um out of uh what we're thinking about there's a in terms of science there are some really amazing innovations that really reflect the singularity of food as medicine Food and Health and the future of nutrition this is just a a partial list of some of the actual uh innovations that are underway I'm showing you this picture uh really to uh spark your imagination because while we're here on Earth we can choose whatever we want to eat but one day when humans become EXT extraterrestrial and we all know the efforts that are underway to be able to get us there it's just going to be us against the environment and the environment outside of Earth is hostile we we'll have to actually take counter measures on a continuous basis in order to be able to protect our immune system protect our bone marrow protect our uh uh our DNA uh the radiation uh from outer space is going to be relentless and damaging so an interesting challenge I'm going to give to you mental framework to think if you really wanted to study food as medicine and nutrition model this uh a future human in living in space and think about what it is when you're start from nothing and when you're and you're pitted against damaging forces what do we need to do to maintain health so this is almost the Ultimate model to think about uh is really how humans will actually live successfully in space so where does that take us well that takes us to real science you can't handwave that answer so I'm going to suggest to you that some of the answers to the Future for food is medicine is going to come out of the pharmaceutical world now I'm a physician and also a vascular biologist I've spent the last 30 years working to help um develop a uh medic medicines that can actually influence angiogenesis which is how the body grows blood vessels it's a common denominator of diseases there's 60,000 miles withth of blood vessels packed inside our bodies it is the common denominator to cancer heart disease stroke blindness obesity diabetes about 70 different disorders um and I can tell you from my work which has actually led to a number of uh FDA approved drugs and devices that there are some amazing insights that I think we can apply to understanding how food can be used as medicine and the reason that we have to tap into this is because of the investment since over the last 25 years 802 new FDA approved drugs we cannot overlook this huge data set this experience this experiential information coming out of the investment in life sciences and so what are we learning from there and this is just a list of 32 of the of of the uh interventions I've personally been involved with and so my street cred is that look science can be turned into practice but it really needs to go through a pretty rigorous process of validation testing and then ultimately figuring out how to actually get it to Market so some of the things that we're learning over the last 25 years in fact is the genome in ways that we've never uh even imagined we could know uh uh previously and now of course we can do Gene editing we've also figured out the human kinome which is you know sort of the interrelationships of of self signaling Pathways and many of the sell signal Pathways um are now druggable targets and this is really the bread and butter of biotechnology and biopharmaceuticals today we've also really more recently um broken through the glass ceiling of immunotherapy where it's now possible to activate um and leverage the body's own immune system to fight disease so now we're not actually treating the disease using synthetic chemicals we're actually leveraging natural cells in fact our own body cells to allow them to actually overcome diseases in some cases very successfully so look at all this information that we've actually gained what how do we apply this to better understand food when you actually have a broccoli shake with even a flu uh vaccine it increases your flu vaccine response by 20 times it makes your body's immune system ramp itself up by 20 times so this is not food versus medicine this is food and medicine so you want to see an amazing explosion of color take a purple potato cut it in half um and put it in a refrigerator it'll just light up for you um uh turns out that that dark purple comes from a natural Dy called anthocyanin by the way same diet in a blueberry as a matter of fact but that purple potatoes been shown whether you bake them whether you make them into chips whether you eat them raw um no matter what you do to whether you mash them they target cancer stem cells which is amazing you know we think of ourselves as human beings but in fact we are a complex we're not just human we're also partly bacteria about 50/50 actually uh and and it turns out that there's a term for humans um that is that we're not even exactly humans anymore we're called called Holo biot h o l o b i o n t a Holo biot is a term used in nature to describe an ecosystem where the whole is not just a single organism but composed of different types of organisms so we are holot you know take me to your leader kind of thing to start I would love to talk a little bit about the general state of health in America as you see it and our standard American diet well um I think that America is one of the most advanced nations in the world for many different areas including Health Technologies but we're really still playing catchup I think uh to many other countries that haven't really changed traditional eating patterns and the and the research that's been going on now is actually taking these quote advancements that started in 1950 in America post-war America and everything became convenient and boxed and ultr processed and Super Con venient and shipped from all corners of the country and all corners of the globe and you know and made to be preserved for months or maybe even years I mean we've evolved over the let let's say last 70 years um into a society a nation that's been further and further from nature hey there I want to share another resource with you it's my free guide on your body's five Health defense systems these five systems and your Genesis regeneration your gut microbiome DNA protection and Immunity are your Shields against disease and they're responsible for maintaining your health every single day of your life by knowing about how these systems work to defend your body you can tap into their healing powers to live a longer better and much healthier life I explain each of these defense systems to you in my free guide and as a bonus I've included some of the best foods you can eat to activate each defense system get my guide for free right now in the caption below now back to the video so I think a lot of the health problems that we have in America uh chronic disease and now not so chronic disease um you know given our experience of 2020 and the pandemic um now of course everybody suffered from it but but you know really um uh in America we've got a we we're we got a long way to go to be able to um have our nutritional status um help our health keep up with actually traditional culture so you know the famous blue zones around the world where um people routinely live to what we what we would call Extreme longevity you know 100 years old and not just old but vibrant and that's what we're looking for we're not looking to just live long we want to live long and prosper I think the Vulcans said that once so what we want to be able to do is to feed ourselves I mean and this is where food as medicine comes in this idea that we are nurturing our body we are taking care of the garden of our body three times a day I mean literally from the time we're born to our very last breath and our health defenses including androgenesis are part of that interconnected part of that ecosystem inside us that we need to have to nurture it's the garden of our body so is that just a really respectful way of saying that we are on the whole definitely not a country with the healthiest habits you know I we we I do think that they the thing about America is it's so diverse and H and there's a lot of different pockets of a lot of different people doing a lot of different things I do think that there are some really extremely fit people who um sort of a subset of people who are committed to eating healthy committing to get enough sleep committing to working out and getting regular exercise so it's really hard in this country to generalize because we are actually so different but as I said I think that there are um sea changes that need to happen and are finally starting to happen in the American diet where you know you asked earlier you know what do we think about the typical Western diet or typical American diet well I don't think we have a typical diet anymore but we did come out of one I think that you know um I know that when I grew up uh sort of on the east coast of the United States um with my parents a lot was about convenience and the things that you saw on television were about the Fantastical nature of the TV dinner or something you could nuke in a microwave and you know it's only later that we look back on this to say you know food that is about as far away from nature as you can make it might not be that good for us or if you're subjecting things into a microwave and heating carbohydrates to a temperature that doesn't naturally exist on Earth with water molecules vibrating maybe we're changing some of those things into plastic and then when we eat them our body can't get rid of it so um you know I think that uh you know like uh I think Society goes into these Cycles where we pretty much got as far as we could with this kind of uh embracement of convenience and technology and now we're swinging back to ask some really fundamental questions that's not to say by the way that there aren't some really interesting and somewhat odd advancements also going on you know the whole um what do they call it uh plant-based meat Revolution that's happening um I'm actually taking look at that and and they're even growing food in a plastic dish in the lab so I you know was I've been part of conferences where because I have a background in biotechnology so I know what stem cell therapy is I've I've helped to try to develop this in you know for biotech companies um from to me I was stunned to hear that you know we can take a biopsy of a salmon and we can grow a fish in a dish that doesn't swim and we can eat it and it kind of tastes like salmon but you know is is that really what we should be doing or is that what's good for our bodies we don't know so I think part of the ethos of of of modern the modern world is on one hand taking care of techn taking exploring technology and taking it to New Frontiers but on the other hand I do think that the science that we have to examine our health is teaching us in many ways that simpler is better and the some of the traditional ways of combining foods to cook it in ways that we've enjoyed for hundreds if not thousands of years in fact is what our bodies evolve to be able to function optimally for given your Decades of research what are some of the best of the best foods for us to eat and how do they work together in synchrony to give us compound benefits I believe in your book you call them your grand Slammers awesome well first of all so in my book EB disease that I write about it's not just about angiogenesis um what I write about is really a a what I discovered so really I I took my experience and research and sort of brought it to the brought it to the to the Forefront and that is when it comes to Food and Health it's not just about the food in fact what I've really discovered is that there's no such thing as a single super food or a single Super Supplement now everybody wants that that's aspiration you know um there's not even a single Magic Bullet drug even okay um but yet we we hear so much about superfoods it gets confusing and I think that um that marketing slogan tends to um dilute the power of what foods can actually do so what I say is when it comes to Food and Health it's not just about the food it's how our body response to what we put inside it and that makes a lot of sense because if you put something bad inside it your body's not going to respond very well going to react poorly when you put something good inside it um our body reacts well so I then asked well what is the definition of Health what why are we healthy why don't we get sick more often and the answer is that our health is not just the absence of disease but it's the result of our hardwired health defense systems that we're born with and they're firing all on all cylinders and from the day we're born into our very last breath what are they androgenesis blood vessels we talked about this already our stem cells when we were kids our grade school teachers taught us that salamanders and Starfish can regenerate but people can't right so that chapter is now being torn out of the Playbook and thrown away the new chapter says yeah humans can regenerate we do regenerate from the inside out slowly but there are foods that can speed that up and enhance it second Health defense system third one our microbiome now everybody's talking about the microbiome I will be the first to tell you that we hardly know anything about it we we are at the tip of the iceberg and this is coming from a research scientist right so scientists tend to know a lot of things that's what people think I I'll tell you scientists are the first people to tell you they recognize what we don't know and I'll tell you that we do know some interesting things about the microbiome there's a lot more to go but we do know that our microbiome our gut bacteria also lives in our skin look lives on our eyes and our mouth and our nose but our gut microbiome actually controls not only inflammation our immune system our hormones our metab metabolism but even our emotions because our gut microbiome can release um there's some bacteria that can actually prompt our brain to release um social hormones one of them being oxytocin which is the social hormone that you see a friend you know and you feel really good by seeing a friend uh that's what your brain releases and makes you feel good more connected with your people it's the same um hormone that your brain releases when you have a good french kiss and also even an orgasm so this is coming from our gut really amazing our gut microbiomes our third Health defense system the fourth one is our DNA which is much more than a genetic code our DNA fixes itself because it's damaged all the time and damaged DNA leads to cancer and other diseases but our DNA is Hardware to fix itself and to slow down its own our cellular aging and of course our immune system which is more powerful than we've ever re ever realized before so what I what I write about in my book are more than 200 foods that activate these body's Health defense systems and while everybody knows there are certain foods that damage our health I've actually figured out which ones are why they damage our health defense systems but more importantly I want to focus on the good things that you should eat because I'm I'm kind of a foodie I love food I wouldn't say I love eating but I I love food and I think food tells us something about our our childhood our culture our families um our Traditions um and so there's an intimate relation ship with our food and the great news is that many Foods um including foods that we mix together and this is the whole point about food synergies activate our body's Health defenses so the grand Slammers uh that I write about my book are a a series of foods and by the way that list is growing because you know you can only put so much in a book and the research continues are foods that activate all five Health defense systems at the same time and so just like a grand slammer you know like in baseball you you know it's a home run in every everybody gets driven around the bases to home um so you score big time that's what I call the foods that actually really knock it out of the park AB absolutely so you know what I've discovered in writing my book and in doing the research is that 95 plus percent of the foods that our body uh craves and that loves to eat because it activates those Health defenses so we we need those Foods are plant-based Foods now plant-based foods are um it's an easy term to say and very popular but there's a lot of nuance to actually plant-based Foods right so um and it's easy to know how Nuance it is when you wheel your cart into a grocery store or if you live in Europe you go to the weekly market and what's the first thing that you see in one of these markets or grocery stores the produce section you're immediately overwhelmed I mean I think that's probably from the time I was a kid you know F going with my mom to the grocery store you go in what's the first thing you see you're surrounded by color greens blues yellows Reds oranges and it changes by the season right and one of my favorite things to do you know when I'm uh going to a small village for example whether it's in Europe or Asia the first thing I do when I arrive you know after I unpack my bags is I go straight to the market right that's one of the first thing I research because I'm so interested in seeing what's there it's it's like it's like space exploration like what's going on you know like I I'm so interested in again most of the stuff you see that you're that you're surrounded by surround sound are plant-based Foods so if plant-based foods are diverse so too are the ways that they can actually help our body's Health defenses and that's where colors make a difference and that's where textures make a difference and where they grow and how they grow whether you treat them as pesticides or not whether um you eat seasonally or not um how you um prepare them even how you chew them can make a big difference in terms of releasing them for example uh we know that a lot of the sulforaphane containing or cruciferous vegetables like broccoli um uh uh they're crunchy right I mean so um I mean even if you still have a little bite to them you shouldn't overcook them if they're soggy you've overcooked them and what happens is that there are um natural bio active chemicals Mother Nature's Pharmacy is actually stuck inside the cells of these plants and for like so for um cruciferous vegetables you want to Chew Chew Chew Chew to break down those plant cells so you can release those natural bioactives so that's one an example a second one is spinach spinach um is um dark leafy green vegetables got a lot of great micronutrients but most people don't realize that one of the more powerful things that spinach contains are natural nitrogen Mo molecules that come out of the soil spinach loves to grow in soil that's got a lot of nitrogen right so we screw up our um soil we're messing up the phosphorus and the nitrogen and we're contaminating it but but spinach naturally absorbs this nitrogen so when we eat spinach and again you don't want to overcook spinach but whether you eat a raw leaf or you sauté it right little bit of olive oil little bit of garlic some shallots or whatever you want to do okay um and you and you eat spinach you don't want to uh you don't want to gulp your food this is where again the Traditions traditional eating is eating with people eating slowly mostly plants enjoying your meal making it tasty because you're combining it all together right so this is now now we're talking about family meal right and you're eating the foods turns out that when you actually chew your spinach and and and enjoy it in your mouth there's microbiome gut back bacteria healthy gut bacteria in our on our tongue they live inside the crevices of our tongue that help to digest the nitrogen coming out of the spinach and then that goes into the saliva that we swallow and that nitrogen goes into our bloodstream now not nitrogen like the bends for for diving this is natural plant-based nitrogen it's nitric oxide and it causes our blood vessels to dilate naturally it causes our blood pressure to go down and it helps our blood vessels to stay healthier and to help his heal from the inside out I want to ask you an even more profound question okay and that question is what is health so um let's go ahead and have you uh uh goad and type in some of your uh question your answers in the chat what do you think health is you know I I used to ask this question myself when I was in medical school trying to figure out like all right what is what is actual Health right so is it absence of disease is it um of Vitality is it Clarity of mind I mean the answers are pouring in and um and and I'm going to actually tell you that although every individual's definition of Health for themselves is may be different and should be different because we're all Unique Individuals and that's one of the importantance aspects of Integrative Medicine is really not trying to copy paste or try to put everybody into a single formula but really trying to include the individualism but I will tell you as a researcher so I'm in internal medicine doctor but I'm a vascular biologist I studi blood vessels and as a scientist I'm always trying to figure out well how do you define something like what does research tell us well health used to be to me if I'm not sick I must be healthy so health is the absence of disease the reason that that's actually kind of a frustrating answer is that we all want better health but actually trying to achieve something that is the ABS of something else okay that's like saying that wealth is the absence of poverty I want to figure out how to get rich well the absence of poverty doesn't give you any answers it's not useful right so so I want to tell you that health is not just the absence of disease that is one part of it but health is in fact the result of our own bodies human bodies hardwired systems of Health defense so we actually have health defenses that are hardwired in our body what do we mean by Health defense well I want to show you this picture most of you guys have seen a castle if not actually having gone to Europe uh or you know you may have been to Disney Disney's got a nice Castle as well but of course everyone you know who's grown up with fairy tales have seen pictures of castles and if you look really closely at a castle there are lots of different elements of castles that are designed for defense in fact almost every aspect of the architecture of a castle is intended for uh defense so let me just kind of share with you a few look at those slits in the column The Columns that's those are Arrow slits for people to fire arrows at Invaders the walls of a castle are slightly sloped which makes it difficult for people to crawl up and I'll show you here's the anatomy of what what's going on there's even a bent entrance so people can't rush in very uh hard the spiral staircase in a castle okay it's interesting it always goes up clockwise okay why does the stairway goes up clockwise think about it if you are if you are a a knight in a castle defending it most people are right-handed so if you're standing defending it and you've got your sword in your right hand you can swing downwards on a spiral staircase that goes up clockwise if you're an enemy and you're right-handed running up the stairs and a clockwise stairs it's much more difficult to swing up okay so every aspect of a castle is is critically uh designed uh to be able to to help defend um all the citizens within well the body is the same same way and I want to share with you the research I've done to look at what is are the bodies The Body Fortress our our our body as a castle what are some of our health defenses androgenesis how body grows blood vessels um our regeneration our stem cells that are in our body our microbiome our gut health healthy gut bacteria we talked a little bit about bacteria in the tongue healthy bacteria there's a lot more lower in the gut our DNA not just a uh uh not just genetic code but actually our DNA is hardwired to protect us from the environment from uh ultraviolet radiation from the Sun from radon from the basement uh from off gassing from our carpet and our furniture and the new car smell and even from the fumes that we would Breathe In when we're pumping gas at The Filling Station you can smell those fumes you're standing down into the gas and all those chemicals that we're breathing in are actually damaging our DNA but fortunately our body can fix itself as part of the health defense and of course our immun immunity like our grandma's always told us how important it is to have a good immune system and certainly after the last two and a half years we are very very alert to how important good immunity is so I'm going to talk about um Health defenses and talk about what they mean for uh diseases but these actually are really amazing because food the food that we eat can activate our health defenses and that's what I'm going to show with you hey there it's Dr Lee I share a lot in my YouTube videos but sometimes we need a deeper more personal dive into how food can be used as medicine and that's why I created my e Tob disease course you'll have me as your teacher and guide to unlock the full potential of food that can be used to boost your health my course is packed with a latest science and practical strategies it's all designed to be easily followed and something you can start using right away so whether you want to prevent a disease or fight a disease or just optimize your health for longevity my course has got you covered so if you're ready to make a positive change click on the link below or scan the QR code on the screen right now I can't wait to see how you're going to get started to improve your health using food now back to the video now I came and worked on these Health defenses and organize these five Health defenses in a very honest way my background is in biotechnology I set out 25 years ago to help develop better treatments for cancer better treatments for heart disease ways to stop vision loss and blindness ways to heal people who have diabetes and what we did uh when I worked with biotech companies okay is to look at these defenses androgenesis how do we develop a better androgenesis drug uh DNA modification how we develop gene therapy regeneration how do we develop stem cell therapy okay immunity how do we develop immunotherapy so each of these Health defenses that I just told you foods can activate are the focus of a number of Drug Company pharmaceutical efforts to develop billion dooll Blockbuster drugs that take a decade and oftentimes don't really work that well and of and many times are not available fairly to every patient and so as I was going through my own work uh over the decades I realized that although I have to tell you I've been successful there I I've been involved with the development of 403 FDA approved drugs for one or more of these types of systems so we have new cancer treatments we have diabetes we have vision loss treatments I'm still working on other ones for heart disease but I will tell you I started to realize that using Pharmaceuticals which are can be lifesaving is really treating the horse out of the barn so I asked if we can we do prevention to prevent the disease in the first place because who wants a chronic disease if we can prevent a chronic disease could we instead have chronic Health that's what I want for my patients and that's what I want for myself when you're talking about prevention you can't really think about drugs you got to think about things that are safe available inexpensive like food so here was the unfair Advantage I had since I worked on these Health defenses from a drug development perspective I had all the tools to be able to throw Foods into these same test systems to be able to interpret the results and to see what foods do and what was really amazing is that when you put them up head-to-head in many case foods can actually beat medicines or at least they equivalent to medicines and in many cases foods can combine with medicines to bring you even more benefits so that's what we're going to um talk about now I want to ask you about uh what do you what are the chronic diseases of greatest interest to you guys what are you interested in go ahead and put into the chat what are some of the diseases that interest you go ahead and put put your own go ahead and put your own interest in what are the diseases that you came to hear about that you'd like to know more about when it comes to food cancer I'm hearing I'm seeing um heart disease cancer diabetes long covid um asthma autoimmune disease Parkinson's look I mean what what's flashing through like crazy like lightning uh uh in this uh is exactly the things that concern me as well concern me as a as a family member I've got family members who are afflicted by the diseases that you're entering here um I'm also concerned about as a doctor I take care of patients with cancer and heart disease and diabetes and uh all those kind of conditions all chronic diseases actually are crushing our health care System man I would like to be able to get to a point where the main work that we do the heavy lifting is really helping people um prevent the disease in the first place and to empower everyone to take charge of their own health why do you need to go to the doctor's office to be able to get the solution if food as medicine might be able to help you take command and Empower you to actually be in charge of your own health so that's what we're going to talk about before we dive into some of the diseases I want to share with you um some information from the CDC the Centers for Disease Control and these are as of last year the um 10 leading causes of death all right um and not surprisingly heart disease is out there cancer is still out there covid kind of goes up and down hopefully going down now and diabetes you know although it isn't a leading cause of death it definitely is a leading cause not a top like top five it definitely is a leading cause of morbidity as well as mortality people with diabetes their quality of life is severely compromised they have vision problems they have nerve problems they have wound problems heart problems kidney problems anybody who's listening who um knows somebody with diabetes understands how important it is to prevent uh and reverse some of those uh some of those shortcomings that that people that people with diabetes are struggling with and I I think it's really important to to say these are people with diabetes I don't refer to them as diabetic patients all right patients are having diabetes and other diseases as well so these I put in The Orange Box I want to share with you some of the work I've done looking at uh how foods can actually activate your health defenses to combat some of these diseases let's start with the bigie the c-word Cancer all right everyone has been touched by cancer at some level in their family this is like the you know that Kevin Bacon uh Game Six Degrees of Separation I would say when it comes to cancer there's almost no degrees of separation or one degree of separation at most but most of us know somebody directly that actually has been touched by cancer it's a word that actually generates fear even among doctors okay and and we are not immune in the medical community from uh cancer uh either but I want to share with you some important insights on that what we have discovered about cancer recently and that is and and that is that one thing that cancer needs to grow to become dangerous is angiogenesis angiogenesis is how the body grows blood vessels um angio blood blood vess blood vessel vessel Genesis is growth one of our body's Health defenses is actually to make sure they can grow enough blood vessels in the body and then stop prevent diseases like cancer from getting extra blood vessels to selfishly feed themselves what do I mean by let me show you a picture all right cancers hijack angiogenesis so take a look at the far left uh upper corner cor there's this little gray dot that little tiny little dle is actually a microscopic cancer why did they form well the human body is made out of 40 trillion cells that have to replicate they have to copy themselves and by the way that's why we're here today and that's why we're still going to be here tomorrow because our body is repeating itself copy and pasting itself now if I asked you to copy and paste something 10 times you're probably going to do it perfectly if I ask you to copy and paste something a hundred times you'll probably do it okay but you might make a mistake or two now we're asking the body the human body to copy and paste replicate cells 40 trillion times almost all in a day okay you can imagine how many mistakes get made I'm going to give you the answer about 10,000 mistakes are made every 24 hours that lead to these tiny little microscopic mutation mutated cells that are tiny cancer so in fact children form cancer adult form cancers healthy people athletes everyone's got cancer in their body it's like a pimple and because you can't see it it's microscopic it can't get any bigger than 2 to 3 millimeters in diameter without a blood supply because no oxygen no food no nutrition the cancer just stays there like a pimple now think about it if you saw a pimple in your face in the mirror in the morning you might stare at it and want to get rid of it but that pimple grew in your back and you couldn't see it you wouldn't even know when it goes away and that's really what we're beginning to understand about the biology of how cancer develops and how our body's um uh defense systems ward off its ability to grow so the question isn't why did I get cancer when you know that that's a very common question that cancer patients ask really the question I want you to ask um is to think about is why don't we get cancer more often right so you're at a bus stop you smell somebody else's cigarett how come you don't get lung cancer you're breathing the fumes if you're standing down when when you're pumping gas how come you don't get lung cancer well there's because your body's Health offenses are preventing those cancers that might form microscopically from Ever Getting to be dangerous and then your immune system Wings by like cops on a beat patrolling a safe neighborhood and sees something abnormal like a drug dealer sitting in the corner might not be doing anything bad but but like a policeman would put the the bad guy into the Patty wagon um the immune cells will gobble up the microscopic cancer and dispose of them that's how we realize um how cancers form and disappear in our body all the time the scary cancers are the ones that actually get a blood supply over months or years a few will actually figure out how to trick our body okay our defenses are down and um and they're able to recruit selfishly a private blood supply and once Cancers get a blood supply they can explode in growth in the lab that I was working in um we found that if you um isolated a tumor from a uh blood supply it would stay small forever essentially but once you let the tumor touch blood vessels a a tiny little small cancer can grow 16,000 times in size in just two weeks so anog Genesis is a big trigger all right what's interesting is that you can actually cut off the blood supply to cancer this is part of the drug development work that I've done in the past and there are now more than a dozen anti-angiogenic drugs that starve cancers by cutting off the blood supply more than a dozen Pharmaceuticals but guess what there are foods that can actually do this as well remember I told you I went from developing drugs to saying could we throw some foods into the systems and see if we get a similar effect and this is in a lab so let me just give you an example of one food that can actually do that tomato actually contains a natural molecule called lopine okay it's a catenoid it's what makes actually Tomatoes red and uh uh lopine when you actually pick a tomato off a Vine and and chew it and bite it like eat it like an apple or cut it into a salad most of the lopin in a form that doesn't get really absorb that well you'll absorb 20% of it 80% of it just go goes out the shoot below okay but if you actually cook it the Tomato the heat from cooking simmering Tomatoes like tomato sauce will change that chemical structure into a form your body loves to absorb like 85% absorption which is exactly what we want for loped now I took lopine and I went to the lab and we tested in a system to see if it would stop those blood vessels from growing towards a tumor in the lab and indeed that's exactly what we found lopine was a potent anti-angiogenic cancer starving molecule okay really quite amazing um and in fact there are research publish Publications on this so I'm not the only person that's done it I I did the work back in 2010 two years later other people replicated it so this is a repeat um of the work that we had done very important the British Journal of nutrition highly credible Journal now remember I told you rubber meets the road is actually what happens with people and here we are the health professionals follow-up study it's a massive study more than 40,000 men studied over 20 years and they looked at nutrition and cancer outcomes and what do they find they found that those men who ate two to three servings of cooked Tomatoes that's tomato sauce per week now how how much was it serving half a cup of cooked Tomatoes okay now think about it tomatoes sauce if I gave you only half a cup of tomato sauce for your pasta you'd probably come back and ask me for a little bit more all right so not much again readily attainable amounts of food eating tomatoes tomato sauce with lycopene in a form you could absorb was associated in more than 40,000 men with a reduced risk in this study of developing prostate cancer by 30% by cutting off the blood supply to prevent cancers from actually growing up and in fact they look at the people who did develop prostate cancer because look 30% didn't get it 70% did they biopsy the prostate and they took a look and here's what they found that those men who did develop prostate cancer when you biop seed their prostate and you compared how aggressive the cancer was how many blood vessels were feeding the cancer those uh uh men who had more tomato sauce um per week over the course of the month actually had fewer blood vessels all right this is anti an androgenic seen in pathology in a research study that really makes a very strong case and that's really why this was published in the Journal of the National Cancer Research in the Journal of the National Cancer Research Institute um that um that Foods the foods that we eat actually can have a meaningful correlation with uh diseases that we care about so for men prostate cancer now there's a there's a similar study for women in breast cancer and the reduction was almost about 40% in a clinical U study looking at a Association now remember I just told you about cooking the tomatoes this has been studied too how long do you have to um change the Tomato to so that's how is available well you know you actually get better bioavailability um by simmering at 190 degrees that's simmering not boiling 212 is boiling and two minutes you've actually converted about half of what you want to do at three minutes you've really transformed a lot you get a lot more bioavailab but you've really kind of supercharged it now we've actually studied this in the human body as well if you cook tomatoes in water right I don't know who cooks tomatoes in water I cook my tomatoes in olive oil by making a sauce but then you were to actually take a look um at the uh you temperature will go up Lop will be changed it will be absorbed in the bloodstream but then you compare how much is is of lopine is in the blood from tomato sauce cooked in water compared to olive oil the oil actually has a lot more now why is that about about three times three times more it's because lopine is what we call a fat soluble molecule lopine um is kind of like soap it doesn't dissolve very well in regular water but it'll dissolve in soapy water and when I say fat soluble I mean it doesn't like to dissolve that e readily in regular water but it'll dissolve in oil really easily so tomatoes and olive oil simmered over a period of time what is what is that Mediterranean Cuisine all right so no no was right when she said eat you know have my pasta with my tomato sauce um it's actually cooked in a healthy way so this is again food is medicine we can actually study it um not just looking at the food to say here's my superfood we're actually able to study the food ask what's in it look at the human look at that and and see how do we study that and look at the correlations this is really what food is medicine is I'm actually one of the people that not only um talks about food and health but actually does the kind of study as well by the way what kind of olive oils do you want to use because olive oils olives contain healthy anti-angiogenic cancer starving polyphenols one of them is called hydroxy tyrosol so how many olive oils are out there well there's a lot of different olive oils which one would you want to pick one of olive oil is from one of these three olives so olive oil monover varial so when I go to the store I have to go to the middle AES right and I look for olive oil what do you most people do you just grab the one that they are familiar with here's what I do I pick up each of the bottles and I look at the side and I look for monovarietal to see if there's any um it tells you what type of olive the olive oil is pressed from and these three marolo from Italy Cori from Greece and picu from Spain the Cori and and pel Greek and Spanish Olive olives are quite common so you can find those in almost any food store you'd go to these days um that's the kind that I used to with my tomatoes because I want extra polyphenols actually from the olive oil as well so again um think about how we know the Mediterranean Cuisine is actually healthy now we're getting down to the science of it as well oh what about the tomatoes is there a tomato that's got higher amounts of lopine absolutely San Marzano Tomatoes uh cherry tomatoes have a lot of lyapin those black tomatoes that only appeared on the market in the last few years a lot of lopeno and ironically Tangerine Tomatoes aren't red they don't look like they'd have a lot of red lycopene die but they already have the lycopene in a form where it's chemically transformed you don't need to cook those you eat those like an apple you'll get a lot of lopine absorbed it's already got the the chemical form of lopine your body can readily absorb so if you want to make a salad and you want to get that lycopene make it with a tangerine tomato which is this kind of yellowish tomato so again you know a lot of people talk about food and health in kind of like a tech spooky sort of way preachy sort of way I love to talk about it in a way that we can relate to because we're going to the store summertime's coming up we're going to see a ton of tomatoes which one are you going to pick hopefully you'll think about this um presentation now a lot of foods with anti-androgenic activity please um come to my website uh sign up for a download I'm G have a gift for you at the very end um or by my book there's tables and charts these are all the foods that we have studied with anti-angiogenic cancer starving activity I want to give you something to take home and um the the first thing I you to think about is that let food be thy medicine is a statement that was attributed to hypocrates 2000 some years ago so this idea although I showed you the science the idea has been around for a long long time so here's what I want you to do at home to make food your medicine this is like my take-home message for you three things three very simple things number one to make food your medicine I want you to start with healthy food I gave you a partial list you saw it you can watch this again on a replay um can see it in my book I'm going to give you a whole list about in a second um choose healthy foods that you already love take a sharpie Circle the ones that you go man I like to eat that one and eat more of it because if you start eating the healthy food that you already love that is healthy you're already way ahead of the game number two cut down or cut out foods that are harmful for your health we didn't spend much time doing that because so many people actually talk about harmful foods so I didn't want to take up your valuable time this evening by telling you what you've heard from everyone else too much sugar too much soda alcohol too much red meat Ultra processed foods processed meats you know what they are cut them cut them down or cut them out and then the final thing is to eat with moderation all right when we overwhelm our metabolism by eating too much think Thanksgiving dinner the seconds you go to First plate great to go back for seconds you Heap up the plate again only two or three forkfuls later man you really regret what you did you're listen to your body um uh you know your body I can't actually handle that so there's a saying called harachi banme stop eating when you're 80% full that's a good rule of thumb eat slowly listen to your body when you think you're going to be about full eat more slowly then stop next time you go to the doctor next time if you're are a physician or a healthc care professional and you're actually sening your patient and like you know we're so busy trying to handle all the medical things or your integrative practice and you're trying to think through how do I actually bring the right Focus to uh my patients think about the kind of Science and the kind of research that I've just talked about and I'll close with this quote from the Nobel laurate Alberton Georgie who once said Discovery real Discovery consists of seeing what everybody's seen and thinking what nobody has thought and what I hope hope I've shown you this evening are some of the foods that we all recognize that we all some of us would just really love to eat those foods and I hope that I've actually stimulated you to think about the same Foods in a new way and that new way tells us about food as medicine thank you very much hi there if you enjoyed watching this video I know you'll love the next one stay here and check it out and I'll see you there