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mYSpdMjkdMM • 4 Foods to Make New Mitochondria (Scientific Proof) | Dr. William Li
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Kind: captions Language: en Here's a truth. Aging does not mean that you have to decline. One of the big problems of people who get older is that they're unstable and they fall. Once you fall, you can break your hip and then you lose your independence. So, you want good muscle strength turns out that can help build your muscles and maintain your muscles. This decline in mitochondrial health, we're starting to realize is one of the underlying causes of fatigue and muscle weakness. Actually, it may wind up being underlying a growing number of age related diseases. People taking your their muscle strength increased by 12%. While placebo group no change in muscle strength at all. [music] Here's a truth. Most of us don't want to think about losing our energy as we get older. And we've seen plenty of examples, maybe even your own family, of people who get older and come across as really, really frail. But here's the thing, aging does not mean that you have to decline. I'm going to start by talking about something called mitochondria. You may have heard about mitochondria already. Uh, and if you haven't, I want to tell you these are little engines that are inside your cells and they're powerhouses. All right? They're like batteries inside your cell. They generate all the energy that your cell needs that your body relies on in order to be able to move and to run. It's all the processes in your body. All right? And when the mitochondria are fresh, just like a fresh battery, they can hold and deliver a lot of energy. But as you get older, just like an older battery, all right, those batteries can wear down. They can lose a lot of their power, right? Like a like a like old batteries in a flashlight, right? the light isn't so bright anymore and your energy can start to fade in your body as your mitochondria get older. And when old mitochondria that are not working that well start to pile up, well, guess what? Your body has a hard time actually generating the energy. This decline in mitochondrial health, we're starting to realize is one of the underlying causes of fatigue and muscle weakness. And actually it may wind up being behind the underlying a growing number of age related diseases. So mitochondria decline. All right. But here's the exciting part. Your body can make a natural substance. It's called uroliththn that can help charge your batteries up. It can help your mitochondria perform better. And the way it does it is by cleaning up all the old, broken down, worn out, not so good mitochondria, right? So, it's like taking all those old batteries out of your flashlight and tossing them out and adding new ones back in. Clear away the old ones so that you can put in new ones. Uh, new healthy mitochondria are going to give you more energy. Okay? So, that way your body will have more battery power, more energy, your muscles will be stronger, you'll have better endurance. This is all science, right? But it turns out human studies have looked at this and researchers at the uh Mizentus and Swiss Federal Institute of Technology in Switzerland, they did a clinical trial. In fact, they did a randomized placeboc controlled clinical trial by looking at 66 healthy adults sedentary. So people are not moving around a lot. These are not athletes, okay? Uh couch potato, let's call it. and they were between the ages of uh 40 and 64, right? Right in that middle age range. And they asked, "What is the effect if you gave these couch potatoes between the ages of 40 and 64 some euroliththn A?" Their body makes it by itself. But what if we gave them the uroliththna to charge them up? So what they did, they gave half of the subjects uroliththn as an oral supplement and they gave the other half of people a placebo. They did it every day for four months. All right? And the results striking. In the group that got the euroliththna, okay? And remember I told you the body makes it by itself. But in this case, they gave supplements to actually boost the uriththna. Guess what? People taking uriththna, their muscle strength increased by 12%. While placebo group, no change in muscle strength at all. So they got 12% extra muscle strength just by taking the the uriththna supplement. The other thing they did is they actually found that people who were taking the uriththna um had better walking endurance. Right? So think about it. You're going out for a walk on a long sidewalk, okay? Um or a hike. Eventually you're gonna get tired. Well, walking endurance is how far you can go. And it turns out um that people who took the uraliththna. Now remember, all of these people were kind of couch potatoes, sedentary. They did not exercise a lot. Guess what? Uralithan a takers, their walking endurance improved by 60 m. Now you might say, "What does that mean? I I can't picture 60 meters." Well, imagine a 20story building 20 stories high tipped on it on its side and walking the length of that building. That's how much more endurance the people with urolithin a supplement actually had. And that makes total sense. If you take uriththn helps to clear out all the old junky batteries so that new batteries can be put in to the body. Guess what? You're going to have fresh batteries, more energy. Now, in the study, the researchers also measured something called V2 max. I know sounds complicated, but let me explain to you. V2 max stands is basically the maximum oxygen intake that your body can uh muster and that's basically how efficiently your body uses oxygen. Right? You need to have energy. All right? That's through your mitochondria, your batteries. Then you need to have oxygen to power up things. And guess what? People who took uriththan a supplement, okay, which clears away all the junk and leaves room for new mitochondria, their oxygen efficiency, their V2 max rose by 7% as well. When they looked at mitochondrial health, how healthy were the mitochondria? Uralithnate takers actually had 22% increase in the health of the mitochondria. Makes sense, right? [snorts] Out with the old, in with the new, 22% healthier. And then the researchers measured something called asocarnitine. All right. Now isocarnitine is a marker of how the body burns fat for energy. All right. And guess what? The asocarnitine levels dropped by 14%. All right? So uralithnan a takers had more efficient ways of using their fat. They didn't actually need to actually um burn fat by, you know, pedal to the metal. they could actually take it easy and still have efficient fat metabolism. And that's because they had better mitochondrial function. And then finally, the researchers looked at a blood marker called C reactive protein. All right, CRP. You might have heard about CRP. It's something that your functional doctor should be measuring. It's a measure. It's a It reflects how much inflammation is in your body. UN takers, guess what? Their CRP levels dropped by 16%. All right, that means that uriththna is also anti-inflammatory as well. That's really interesting, right? Well, and the reason I'm telling you is because I was skeptical about uriththna supplements and mitochondria for a long time. But I'm a scientist and really a good scientist always starts with having an open mind. So you might be skeptical about something, but let's look at the data. And I just showed you the data. Uralithna A actually improves human parameters that you can measure that reflect better mitochondria and less inflammation. Okay, so without a supplement, I told you your body already makes uriththna. Where does it make it? Well, turns out uroliththna is made in your gut. And how does your gut make it? Well, it makes it from food. Foods that contain natural bioactives called elagitanins and elagic acid. All right, that's E L L A G IC. Elagic acid or elagitanins is E L L A G I T A N I Ns. Elagitanins. All right, these this is the starting block to make uriththna naturally in your gut. So what are the foods that contain elagic acid and your elagitians? pomegranate, walnuts, berries, raspberries, strawberries, blackberries. You eat those foods, pomegranates, walnuts, strawberries, blackberries, raspberries. You are feeding your body with the substrate, the starter material for your gut bacteria to make uriththn. And when you eat them, guess what? Your gut microbiome goes to work. transforms the elagitanins uh and elagic acid into uraliththna that gets into the bloodstream. It goes circulates throughout the body and guess what you wind up actually having more fresh mitochondria more energy in your body. That is a good thing. What's interesting is that not everyone does this metabolism to create autanin into your lithin the same way. Some people's microbiome are better at doing this than others, but everybody benefits from eating those foods like pomegranates and berries I told you about and walnuts. But you know, you should eat those foods anyway because they deliver other polyphenols and dietary fiber and anti-inflammatory substances that activate your health defenses and lower inflammation. Uralithna really important for energy. And if you get it from pomegranate, um you can add some pomegranate to your yogurt, for example, or crush up some walnuts and sprinkle it onto your salad. It's a great way to actually uh get the the the uh foods that actually give the starter material for uralithna. Or one of the things I love to do is just have a bowl of berries for breakfast. I'll have a cup of coffee, maybe a cup of tea. Uh depends on my mood, but I often go for coffee. Sometimes I'll just fix myself a bowl of berries and that's pretty much it. If I can get a whole yogurt, I'll do that as well. But berries, you can also toss into a smoothie if you want a smoothie as well. Okay, so the other thing is I told you not everyone's uh gut bacteria work the same way. Some people are not good metabolizers of autanins and that's where you can actually get um benefit from taking a uraliththn a supplement. There's one called mopure. If you want more energy, it might be a good idea to take that anyhow. And it's been studied in human studies and shown to boost the mitochondrial function like the way that I told you about earlier. All right? But this is actually what you want from a supplement. You want to know that it actually works. And uh clinical trials were actually done. So one of the trials uh researchers actually gave might appear to older people who took the um uraliththan a uh supplement every day for four months or placebo. And these were people who were just average physical shape and endurance. The researchers measured their mitochondrial function at the beginning not so good. So they were like suboptimal mitochondrial function. These people were not feeling particularly energetic. They you know they were um a little fatigued before they started study. Then they gave them the uriththna mipure. And after four months guess what they found? The people who took the uriththna supplement the mighture had better endurance. They had more energy generated by their muscles. Their mitochondrial function was better in blood tests. And then they actually biopsied their muscle. That's a pretty serious clinical trial. All right? And when they biopsied their muscle, guess what they found? They found that the gene expression, in other words, at the cellular level that the people who took the uriththna, they had more mitochondrial genes that were activated as well. That's pretty definitive. All right. Uh, and by the way, the uroliththnan a uh stimulated mitochondria worked even better if you combine the supplement with exercise. Exercise stimulates your your mitochondria uh as well. All right, so clinical trials works well. It's pretty amazing, I think, uh, for activating your mitochondria. Okay, next I'm going to tell you how to improve your muscles directly. All right. And the reason that you need to know about this is because look, after the age of 30, most people start losing muscle mass. Between uh five to 10% 3 to 8% of their muscle mass with every decade. All right? That means by the time you're 50, you've probably lost about 20% of your overall muscle mass compared to when you're in your 20s and 30s. All right? And by if you keep on going 60s7s now you're losing so much muscle mass that you're going to be weaker. So you don't want that. You want people to you want yourself to actually have muscle mass and you want and you want to actually look like people who are able to maintain their strength. Loss of muscle is loss of strength. Loss of strength means imbalance. And you know one of the big problems of people who get older is that they're unstable and they fall. Once you fall, you can break your hip and then you lose your independence, right? So, you want good muscle strength. Really, really important. But there's some good news. It turns out that omega-3 fatty acids, which you can take as a supplement or you can get in seafood, can help build your muscles and maintain your muscles. All right, Omega-3s, you know, these are the healthy fats you find in oily fish, salmon, mackerel, sardines, but you can all find them in all kinds of seafoods, including squid and shrimp, lobster. You can all get crab all has omega-3s. Uh clams, and if you're a vegetarian or a vegan, you can also get omega-3s from eating plant-based foods like flax seed, chia seeds, walnuts, soybeans. In that case, you are getting the precursor to omega-3s called ALA that your body will start to uh create its own omega-3s, right? So, we think we know omega-3s are good for heart health. We know they're good for brain health. Now, research shows that they're good for muscle health as well. So, I want to tell you about the research and this is researchers from the Taipei Medical University in Taiwan. They analyzed all the data from 12 high quality randomized clinical trials um looking at omega-3s. All right. In total in these 12 trials, more than 2,000 adults age 60 and older. All right. And they also um were asking the question people who were eating omega-3s, also known as PUFAs, polyunsaturated fatty acids, was there any connection between the amount of PUFAs or omega-3s they were eating and muscle uh mass and muscle strength. And here's what they found. The people who consumed the most omega-3s had a 2% increase in their muscle mass and they had a 4% increase in their hand grip strength. All right, that's a reflection of how of your overall muscles and they had a 5 to 6% better performance in the chair rise test. What's a chair rise test? Well, guess what? If you're sitting in a chair and I said get up, what would you have to do? You would have to push the chair back. Then you have to raise yourself up and stand up straight. That actually takes muscle strength. So now you might be saying at this point 1 to 2% muscle mass improvement, 2 to 4% improvement in hand grip strength, 5 to 6% performance in chair rise test doesn't sound very significant, Dr. Lee. Well, it's true. Those percentages are small, but it might not seem like a big deal, but think about it. Hand grip strength isn't just about opening a jar of pickles. Hand grip strength predicts your ability to walk smoothly and not fall, to climb up a set of stairs without losing your balance and tumbling down, and even to be able to live independently. All right? So, every bit of mobility, every bit of strength makes you able to be more independent, to walk unaded. You don't need a cane. And guess what they found? These researchers found they found omega-3s help maintain the muscle mass and power. Now, how do omega-3s work? Well, they work in a couple of different ways. One of the most important is that omega-3 fatty acids lower whole body inflammation. When you're inflamed, your whole body, guess what? Makes you feel weak. All right? So, this is like more than just affecting the muscle affects everything. You're just feeling weaker. So, omega-3s reduce the inflammation, which actually makes you come out of your shell, your inflammation shell to be a little bit stronger. Omega-3s also improve neuromuscular function. Now, your muscles are powered by nerves. Nerves are like the wiring, okay? Like the wiring in your wall that activates a machine. The machine being the muscle. But neuromuscular function is a connection between the nerves and a muscle. Omega-3s make that nerve conduction to the muscle to make it contract, work better. And omega-3s also turn on more protein synthesis in the muscle itself. So, the muscle can grow. Muscles are made of protein. You're going to grow your muscle. You need the muscle needs to make more protein. Omega-3s can actually do that. All right? And by the way, when you do resistance training, you take a protein supplement, and then you add omega-3s, all right, it actually powers up. Taking omega-3s will make resistant training or taking protein uh supplements, protein powders work even better to maintain muscle mass. So, what are my pro tips for you? My pro tips are eat more omega- foods. salmon, mackerel, sardines. Now, if you want plant-based version of it of omega-3s, flax seeds, sprinkle them onto your yogurt or your salad, walnuts, snacking on them. Those are plant sources of the precursors for omega-3s that your body will make, ALA. The other thing you could do is take a high quality omega-3 supplement. Okay? You want to get a formula that's rich in EPA and DHA, and combine that with exercise. Remember I told you omega-3s with exercise help to build muscle even better, right? So do a little with strength training. You can use a resistance band or, you know, lift weights. Make sure that you're getting somebody to show you how to do it properly so you don't hurt yourself. But that will also along with omega-3s help you maintain muscle mass. So a lot of people are, you know, really concerned about protein these days. I'm telling you, exercise, omega-3s also a critical way to be able to do it. That's very, very science-based. When it comes to muscle mass, you want to be proactive and not reactive. You don't want to wait until you lost muscle before you try to build it back. You want to just keep it. Muscle health is the key to longevity and good quality of life. That's what you want. All right? So, anybody tells you getting old means you're going to get frail? Not necessarily. So, you can keep your muscle mass there and you can actually keep your muscles in a more youthful shape so you can be strong and active into your 70s and 80s and even beyond with omega-3s. All right. Finally, I want to share some research that well revealed something that I thought was unexpected. And it's a discovery that I want to tell you about melons. You know, cantaloupe, honeydew, even watermelon. All right. Turns out melons can help your body fight fatigue and stress, specifically oxidative stress. And this research comes from um a scientist at the University of Mont Pelier in France. The French are very interested in their melons. They have some amazingly sweet melons uh grown in their fields. And what these researchers did is they conducted a double blind placeboc controlled trial where they tested melon extract. So they grew their beautiful melons. They extracted it. What they found is that melon extract was rich in super oxide dismutase SOD. You might say, "What is SOD?" Well, look, SOD is like a fire extinguisher that when you have it in your body that you can get from eating melons, it'll actually put out the fire from oxidative stress that can damage cells. So, think about, you know, chemicals uh chemical exposures, ultrarocessed foods, um environmental exposure that cause a lot of extra uh oxidative stress. There's like sparklers going off in your body, damaging cells. Well, guess what? SOD is like the fire extinguisher that puts that out. So what you want to do is you want to actually neutralize the oxidative stress which can cause fatigue and cause cellular aging and you want to neutralize it with SOD. Okay. So in this clinical trial, the researchers gave the participants melon extract every day for 4 weeks or they gave them a placebo. And here's what they found. The in the melaners the in their body the antioxidant defenses, okay, the SOD activity increased by 18% just in four weeks. So they got a lot more neutralization of the cellular stress. And in fact, the having the melanext made the oxidative stress go down, which is just what you would expect. and the damage to the proteins in the body also went down by 10%. This is an extract from melons like a cantaloup like melon. So why does this matter? Okay, well first of all if you like cantaloupe or other types of melons like me honeydew then you're in luck. This is actually good for you. But the other reason is because our bodies constantly put under stress. Aging causes stress. Pollution causes stress. Poor sleep causes oxidative stress. microlastic that you're uh eating and drinking from packaged food causes uh cellular stress. Ultrarocessed foods with all those additives causes cellular stress. Everyday wear and tear causes oxidative stress over time that kind of degrades your body and that chips away at your energy. So if you want to recover, you want to protect yourself against that, guess what? Good news is that eating melon, okay, can help boost your SOD defenses to neutralize all those stressful harms without needing to go to an extreme. What are some of my pro tips from this research? Well, the next time you go uh to the store, the grocery store, the farmers market, and you see melons, okay, especially seasonal melons, go ahead, buy one. Cantaloupe, honeydew. I love them. All right, you're going to buy honeydew. What you want to do is you want to press the ends a little bit and see if it actually is a little bit soft. All right, when the ripe ones are a little bit soft, then smell it. It should smell really good like a a melon. What I like about melons, they're not particularly sweet, so you're not getting a huge sugar load and you're getting hydration. Getting hydration is critical to prevent from being fatigued. When you are dry, dehydrated, you're going to be tired. So, melons, more than 90% water, packed with vitamin C, anti-inflammatory, all these SOD uh activators going to give you more energy. I could eat a melon for breakfast, and sometimes I do. Just cut them up and you can throw them into yogurt if you like, or just eat them plain. I love to eat just plain fresh uh yogurt. Or melon's a great choice for dessert. You don't need to have cake or pie. Go ahead and have some melon. This is what they do in Asia at the end of a fancy banquet or dinner. Sometimes I'll bring out some fruit. Melons are a good choice. By the way, that SOD, that neutralizer of cellular stress, there's other foods that also have it as well besides melon. Want to know which ones? Spinach, broccoli, and green tea also have SOD activity for your body as well. Staying strong as you age isn't just about lifting weights. It's about what happening inside your body from your mitochondria. You want the mitochondria, old ones to be out, new ones to come in, give you that cellular energy. You want to lower inflammation because inflammation makes you tired. And you want to actually neutralize cellular stress and activate your health recovery systems so that you can actually be energetic uh as you age. All right. Now, if you found this video helpful, hit the like button, subscribe to my channel, and forward this to somebody that you feel would find this super useful, and maybe you can help them with their own health. So, I will see you in the next video. Dr. Lee out. Hey, if you like that video, then you're going to love this one. Check it out.