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eW4ypjY_eXo • Why Antibody Tests Don’t Yet Reveal Coronavirus Immunity I NOVA I PBS
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Kind: captions Language: en could this blood test tell if you're immune to kovat 19 in recent weeks seems like everybody's been talking about those antibodies antibody antibody tests antibody tests have taken center stage as the crucial new tool for understanding how widespread the pandemic is and recently did you get your blood drawn a lot no I was lucky enough to be tested to see if I have these highly sought-after antibodies and we're going to do some analysis on the antibodies but what are these antibodies and what do the results really mean so I do call antibodies magic bullets I might not be the only person in the world that caused the magic bullets delete alter is an antibody aficionado in normal times she studies how these magic molecules work essentially what antibodies are are the immune system's ability to make molecules that go around the entire body survey all the different tissues and then as soon as antibodies see a pathogen they will stick on to that surface and they will mark that surface the entire immune system knows that there is something going on with that particular cell and that pathogen must be destroyed and here's the neat thing about antibodies after they evolved in your body to take out specific pathogens they then stick around in your blood for a while leaving an archive of what you've been exposed to and therefore what you might be immune to my laboratory has been focusing on the development of tools that can tell us how much antibody to coronavirus we have in our blood by looking for antibodies you could tell if somebody had seen that virus even if they were no longer shedding that virus in Boston Goleta is working with Duane Wiesman to study hundreds of blood samples to see who has antibodies and if they make people and moontak over 19 are bringing we actually delivered samples to gleep when we were filming with her okay that's a good absolute how I lucked into getting an antibody test so your blood sample was initially received by our laboratory and then we ran your plasma samples against the virus and we asked which antibodies are binding to the virus and so when we check your sample we found that there was no binding to any of these I see that you are a bit disappointed by this I had felt a little sick back in March and the thinking was well if I had been exposed then maybe I already got it I'm already immune I should say too that even though we want to have antibodies to this virus it's not clear the degree to which having antibodies to the virus will protect us from an infection it is not that just by having a positive antibody test that you are automatically ready to re-enter the population the last thing we want to do is to tell somebody that they have antibodies have them re-enter the workplace have them re-- exposed and for reasons that we cannot completely understand develop much more severe disease so if these antibody tests can't tell if someone is immune what are they good for we don't understand how many people in the general population have truly been exposed or infected even without their own knowledge what we really need is these tools that would give us a much better understanding of who had been exposed and who was infected my test was just part of a larger study the only thing it tells me personally is that I was not exposed but getting this sort of information on a larger scale will tell us how widespread the viruses and we'll also start to understand what that precious immunity actually looks like for that lots of people need to be tested and tracked to understand which antibodies and at which levels confer immunity and for how long so let's say hypothetically speaking we could get a group of a hundred individuals that all had antibodies to this novel coronavirus and let's say that we could group them into those who had high levels or medium levels or low levels and let's say we could study them over a given period of time we could look at the number of infections that reoccur individuals in these different antibody categories and what are the characteristics of an antibody that makes somebody immune to the infection this type of analysis allows us to do now for the first time is to define the absolute threshold or the level of antibody that gives you complete protection from disease that is if antibodies took over nineteen do indeed make us immune at all which most experts agree is likely but not certain so when will we have these Mindi tests when will I be able to go to the grocery store and know that I can touch everything on the shelves right I know that's your dream to go to the grocery store and everything because whatever you can that's just the thing you want to do now right it will take some time to make sure we understand the quality of the antibody tests and to understand what it really means to have antibodies to the virus until we understand what really it means to have antibodies it's good to play it safe I get it hearing we don't know yet is not a very satisfying conclusion I wish my blood test could have told me I'm safe we all want to get back to normal but before we can do that we need to learn a lot more about this virus and scientists all around the world are racing to do just that so for now most public health experts say staying home is the best way to keep yourself and those who stay home safe and if you want to learn more about what scientists are discovering check out Nova's decoding Cove at 19