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35Ik187lryQ • This University is Using Saliva Testing to Monitor the Spread of COVID-19 I NOVA I PBS
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Kind: captions Language: en you pretty much just spit into this tube and it goes up so slowly it takes maybe like two three minutes tops and then you put it in a container and you get your results in like 12 hours the university of illinois is trying to control the spread of cobin 19 by collecting spit illinois testing is i mean that has been one of the major innovations of our time and as far as large public universities have gone flexible universities have gone illinois has been able to keep its case count lower than a lot of places that we would expect uh it to sort of follow like the university of georgia or the university of texas that kind of thing the u of i implemented a mandatory screening program that tests students for the coronavirus two or three times a week it's one of the largest programs in the country using a saliva based test created in-house and one of the only mandating frequent testing and that's fairly fairly uncommon amongst universities most universities are opting for only symptomatic testing so testing students when they start to exhibit symptoms that's a massive issue because of how we know this virus spreads most people in that age group in the 18 to 25 year old age group who get covet 19 will be asymptomatic so if you're testing only symptomatic people you're not going to catch the disease as it spreads the u of i built an entire system for testing campus goers centered around a coronavirus test that samples the amount of virus in saliva students need proof of recent negative test results to gain access to campus buildings it says granted and that means i've had a recent negative test so for the undergrads if you haven't had a negative test in three days it says deny and they can't get into a building if students do test positive they get a push notification on the app and are put into isolation either in an isolation dorm or a hotel room we have had students with symptoms but we have not had a student hospitalized and of course that that means there have been no student deaths while the testing is central to the university strategy building a new culture on campus has been a large part of the effort to control the spread of the virus socialization and culture are really important when it comes to this virus culturally it's it's hard for students to buy into testing when they know they have to go get get get their brain picked every every week or so they simply planned earlier and better than i would say everyone else in april researchers started developing a test that didn't require the supplies needed for a nasal test things like swabs and solutions that were hard to find earlier this year due to a national shortage if you heat the saliva at 95 degrees c for 30 minutes it does a few really really important things one is that it inactivates the virus secondly it enables the genetic material to be accessible and thirdly it inactivates the components in saliva that are inhibitory to pcr pcr or polymerase chain reaction is a method researchers use to detect the coronavirus by amplifying and looking for the viruses genetic material rna scientists found that heating up the samples prepares it for the pcr process without all of the reagents needed for the nasal swab with the addition of one buffer the sample is ready for pcr so we don't need a swab we don't need the viral transport medium and we don't need the rna isolation kit all of those are gone and so we don't have any of those supply chain bottlenecks that's also why our test is so cheap because we don't have to pay for any of those things so and also why it's so fast the test also gives information about viral load or how much of the virus is in a sample that information coupled with a record of recent tests can be key in identifying how long someone has been infected we actually get a quantitative readout of how many copies of the virus per milliliter of your saliva and so we've been using that ct value it's called the cycle threshold which is a direct readout of the concentration of the virus to help make decisions if you've got 15 negatives in a row and now all of a sudden they just flip positive that means you caught them on the way up so it's context dependent testing everyone who comes on campus multiple times a week is no small undertaking their labs run around the clock often processing more than 10 000 samples a day one in 50 covet 19 tests in america happens at the university of illinois every day i want to be very clear here not 1 in 50 tests on college campuses in america 1 in 50 tests in america happens at the university of illinois while the testing has been key to controlling the spread of the virus it hasn't stopped the spread when students returned to campus for the fall term there were two big spikes in cases one researchers predicted the other an unwelcome surprise so we modeled that seven to eight thousand students would go to parties two or three times per week and we modeled that they might not wear their masks all the time at their party so we knew this was going to be a challenge and we still predicted we'd be in really good shape what we didn't model however was that students who knew they were positive would still go to a party or if they knew they were positive they would host a party in their house and that's what got us that's what surprised us county contract tracers have found that most cases in undergrads stem from either social gatherings or from where they live there is no evidence of infection in class there's no clusters by class group and university researchers don't think that infections among the student population are spreading to faculty and staff or to the community around campus the student group tends to infect amongst themselves and then the faculty and staff what we see is infections acquired in the community now as cases rise across the u.s researchers are noticing an uptick on campus too adding to growing concern about the holidays having everybody leave and then come back is one of the biggest challenges chances are it's going to be a very challenging event it's almost like we saw when they all came back the first time you know they bring back a lot of cases with them so our hope was that they would a lot of them would just choose to stay home that said we've been doing lots of surveys and turns out a lot of them are coming back i think we all have to recognize we're in for a really tough next three months or so the new normal is we have to rethink how we socialize we've got to do it differently [Music]