This Powerful Psychedelic May Help Treat Opioid Addiction | NOVA | PBS
wMqWtIachd8 • 2024-10-01
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a powerful psychedelic called ibigan is
making headlines and there's growing
evidence that it may help treat opioid
addiction and even traumatic brain
injuries so iban's different than the
other psychedelics in the sense that
iban seems to be able to abort the
actual withdrawal phenomenon it's a
treatment showing early promise but it
can be dangerous too including some
serious side effects like cardiac arrest
and even death it's not really a
recreational drug to be taken lightly
ibigan comes from the root bark of the
aboga tree which is native to the
rainforest of central Africa and has
been used by indigenous communities in
Gabon and Cameroon in traditional ritual
practiced for thousands of years it was
first studied in the US during the early
60s but like many other psychedelics was
banned in 1967 in recent decades there's
been a renewed interest in studying
ibigan in the US funding has been
limited to animal studies since it's
still illegal for human use but in other
countries it is legal or unregulated and
what they found has been surprising some
small International Studies have claimed
that IA gain can help reduce or even
eliminate symptoms of withdrawal in
people with opioid addiction there's
early evidence that ibigan may also help
people with brain injuries a group of
researchers conducted a small study of
30 men who were in the US Special
Operations forces and had sustained
traumatic brain injuries in addition to
self-reported questionnaires
neuroschistosomiasis
control group for comparison and other
research shows that the use of some
psychedelics like LSD may actually
permanently rewire the brain brain scans
show that during use some psychedelics
can temporarily create connections
between regions of the brain that don't
normally talk to each other one thing
that makes ibigan unique is the duration
of the drugs effects which are believed
to be more than 24 hours that longer
period gives the brain more time to
rewire itself and respond to treatment
by comparison the effects of psilocybin
the active ingredient in mushrooms
typically last up to 6 hours and
mesculin and peyote about 8 hours people
who have taken iaame reported
experiencing a waking dreamlike state
where they can revisit parts of their
past and it produces a very stereotyped
set of experiences where people have
this Life review or slideshow where they
go back through earlier life um
emotionally salant memories and they
kind of re-evaluate them today iaan is
still illegal in the US for use in
humans and remains classified as a
schedule one drug along with heroin and
LSD like other psychedelics using ibigan
can cause arhythmia and a regular
heartbeat that in some cases can lead to
cardiac arrest and even death some
researchers are working on ways to mimic
the effects of ibigan in the brain the
goal is to treat addiction and
depression but without leading to
complications the new molecules although
they don't look like a ban at all they
do the same thing mechanistically that a
Bogan does and they at least in the
animal models they they copied what
eog's effects are but ibigan research
still has a long way to go we have this
very exciting idea that you know
psychedelics and especially iigame
should be you know able to uh cure all
of these diseases of the brain but we're
very much at the beginning of those
types of studies
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